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나이관련황반변성에서 발생한 맥락막신생혈관 환자에서 반복 시행한 광역학치료의 효과

Other Titles
 Photodynamic Therapy for Choroidal Neovascularization Secondary to Age-Related Macular Degeneration 
Authors
 김현웅  ;  노영정  ;  김하경  ;  김인택  ;  김시열  ;  권오웅  ;  곽형우  ;  고형준  ;  남우호  ;  강세웅  ;  유형곤  ;  문준웅  ;  박규형  ;  변석호  ;  송수정  ;  안재균  ;  엄부섭  ;  오재령  ;  유승영  ;  윤일한  ;  이성철  ;  이원기  ;  이재홍  ;  이정희  ;  이지은  ;  이태곤  ;  최광주  ;  함돈일  ;  허걸  ;  정흠 
Citation
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.48(6) : 789-798, 2007 
Journal Title
 Journal of the Korean Ophthalmological Society  (대한안과학회지) 
ISSN
 0378-6471 
Issue Date
2007
Abstract
Purpose: To investigate the effects of repeated photodynamic therapy (PDT) for subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD) in Korean patients. Methods: Clinical data of patients who were treated with repeated (3 times or more) PDT for subfoveal choroidal neovascularization secondary to AMD and followed up for more than 6 months were collected from 17 hospitals around the country. Visual outcomes at 12 and 24 months, follow-up were compared between subtypes of choroidal neovascularization. The factors related to final visual prognosis and PDT-related adverse effects were evaluated. Results: 244 patients (244 eyes) were recruited (male: 60%, age: 67.7±9.1 years). The portion of patients with predominantly classic, minimally classic, and occult without classic choroidal neovascularization was 57%, 13%, and 24%, respectively and that of patients with visual improvements or less than moderate visual loss at 24 months follow-up were 28%, 38%, 30% and 47%, 56%, and 65%, respectively. Baseline visual acuity and age were significantly related to the final visual prognosis (p<0.05). PDT-related adverse events developed in 15 (6.1%) patients, but most were mild and transient. Conclusions: Repeated PDT for subfoveal choroidal neovascularization secondary to AMD has effects comparable to those of previous prospective, controlled trials without any significant safety concerns in Korea.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kwon, Oh Woong(권오웅)
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96636
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