Cited 15 times in
Accuracy of fluorodeoxyglucose-positron emission tomography for diagnosis of single bone metastasis: Comparison with bone scintigraphy
DC Field | Value | Language |
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dc.contributor.author | 서진석 | - |
dc.contributor.author | 유영훈 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 윤춘식 | - |
dc.contributor.author | 허진 | - |
dc.date.accessioned | 2014-12-21T16:45:07Z | - |
dc.date.available | 2014-12-21T16:45:07Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0363-8715 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/96285 | - |
dc.description.abstract | PURPOSE: The aim of this study was to compare the accuracy of fluorodeoxyglucose-positron emission tomography (FDG-PET) with bone scan for diagnosis of single bone metastasis using a semiquantitative method. MATERIAL AND METHODS: Seventy-six patients with suspected single bone metastasis, who underwent both FDG-PET and a bone scan, were selected. The number and location of lesions detected upon both FDG-PET and bone scan were recorded, and the lesions were compared using the McNemar test. For semiquantitative analysis, a maximum (max) standard uptake value (SUV) of 2.5 was used as the positive cutoff value for metastasis. The difference in max SUV value among 3 groups (osteolytic, osteoblastic, and benign lesions) was assessed using the Student-Newman-Keuls method. Biopsy results, other imaging findings (multirow detector computed tomography, magnetic resonance imaging), and the patient's clinical course were used as references. RESULTS: There were 47 single bone metastases and 29 benign lesions. The sensitivity, specificity, and accuracy of bone scans for diagnosing bone metastases were 89%, 41%, and 71%, respectively, and those of FDG-PET were 85%, 52%, and 72%, respectively. These data were not significantly different (P > 0.05). Using a max SUV of 2.5 as the positive cutoff value for metastasis, the specificity and accuracy of FDG-PET, 83% for each, improved. When classifying bone metastasis as osteoblastic or osteolytic, the max SUV was significantly higher in osteolytic metastasis than in osteoblastic and benign lesions (P = 0.001). CONCLUSIONS: Fluorodeoxyglucose-positron emission tomography (FDG-PET) using the semiquantitative parameter SUV improves the diagnostic ability to differentiate between single bone metastases and benign lesions. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 812~819 | - |
dc.relation.isPartOf | JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Bone Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Bone Neoplasms/secondary* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorodeoxyglucose F18* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Interpretation, Computer-Assisted | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Positron-Emission Tomography* | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Radiopharmaceuticals* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Accuracy of fluorodeoxyglucose-positron emission tomography for diagnosis of single bone metastasis: Comparison with bone scintigraphy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학) | - |
dc.contributor.googleauthor | Jin Hur | - |
dc.contributor.googleauthor | Choon-Sik Yoon | - |
dc.contributor.googleauthor | Jin-Suck Suh | - |
dc.contributor.googleauthor | Mi Jin Yun | - |
dc.contributor.googleauthor | Young Hoon Ryu | - |
dc.identifier.doi | 10.1097/rct.0b013e318031cc4d | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01916 | - |
dc.contributor.localId | A02485 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A02615 | - |
dc.contributor.localId | A04370 | - |
dc.relation.journalcode | J01350 | - |
dc.identifier.eissn | 1532-3145 | - |
dc.identifier.pmid | 17895798 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200709000-00027&LSLINK=80&D=ovft | - |
dc.subject.keyword | bone metastasis | - |
dc.subject.keyword | fluorodeoxyglucose- positron emission tomography (FDG-PET) | - |
dc.subject.keyword | bone scan | - |
dc.contributor.alternativeName | Suh, Jin Suck | - |
dc.contributor.alternativeName | Ryu, Young Hoon | - |
dc.contributor.alternativeName | Yun, Mi Jin | - |
dc.contributor.alternativeName | Yoon, Choon Sik | - |
dc.contributor.alternativeName | Hur, Jin | - |
dc.contributor.affiliatedAuthor | Suh, Jin Suck | - |
dc.contributor.affiliatedAuthor | Ryu, Young Hoon | - |
dc.contributor.affiliatedAuthor | Yun, Mi Jin | - |
dc.contributor.affiliatedAuthor | Yoon, Choon Sik | - |
dc.contributor.affiliatedAuthor | Hur, Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 31 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 812 | - |
dc.citation.endPage | 819 | - |
dc.identifier.bibliographicCitation | JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.31(5) : 812-819, 2007 | - |
dc.identifier.rimsid | 35034 | - |
dc.type.rims | ART | - |
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