We present a new intraocular lens (IOL) fixation technique that reduces the presence of intraocular knots and eliminates the need for scleral flaps while attaining excellent central positioning of the IOL. It also provides rapid visual rehabilitation from the insertion of a foldable IOL through a small corneal incision. This single-loop suture technique is an easy, convenient, and practical procedure, with minimum complications in the treatment of aphakia and the management of cataract surgery in eyes without capsular support