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Cytocompatibility and electrochemical properties of Ti–Au alloys for biomedical applications

Authors
 Keun-Taek Oh  ;  Dong-Kuk Kang  ;  Kyoung-Nam Kim  ;  Good-Sun Choi 
Citation
 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol.83B(2) : 320-326, 2007 
Journal Title
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
ISSN
 1552-4973 
Issue Date
2007
MeSH
Alloys/chemistry* ; Alloys/toxicity ; Animals ; Biocompatible Materials/chemistry* ; Biocompatible Materials/toxicity ; Corrosion ; Electrochemistry ; Fibroblasts/drug effects ; Gold Alloys/chemistry* ; Gold Alloys/toxicity ; Hardness ; Materials Testing ; Mice ; Titanium/chemistry* ; Titanium/toxicity ; Alloys/chemistry* ; Alloys/toxicity ; Animals ; Biocompatible Materials/chemistry* ; Biocompatible Materials/toxicity ; Corrosion ; Electrochemistry ; Fibroblasts/drug effects ; Gold Alloys/chemistry* ; Gold Alloys/toxicity ; Hardness ; Materials Testing ; Mice ; Titanium/chemistry* ; Titanium/toxicity
Keywords
titanium (alloys) ; cytotoxicity ; corrosion ; biomaterials availability ; mechanical properties
Abstract
The purpose of this study was to develop Ti–Au alloys with a higher resistant to corrosion, better biocompatibility, and better mechanical properties than the commercially pure titanium and its alloys. Ti–Au alloys were designed with a gold content that ranged from 0 to 5.0 at % in steps of 1.0 at %. Properties of the alloys including chemical composition, microstructure, phase, hardness, electrochemical properties, and the cytotoxicity were investigated. Only the α phase existed in the Ti–Au alloys. The addition of gold to the titanium decreased the α to β transformation temperature. The acicular α phase became thinner and the hardness value increased with increasing gold content. In the electrochemical tests, Ti–Au alloys had a higher resistant to corrosion than had pure titanium and did not exhibit pitting corrosion in artificial saliva. The cytotoxicities of the Ti–Au alloys were similar to that of pure titanium. Therefore, Ti–Au alloys could be used as biomaterials in the medical and dental fields.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.30798/abstract
DOI
10.1002/jbm.b.30798
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyoung Nam(김경남)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96237
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