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제2형 당뇨병환자에서 나테글리니드가 식후 고혈당 및 산화성 스트레스에 미치는 영향

Other Titles
 The Effect of Nateglinide on Postprandial Hyperglycemia and Oxidative Stress in Patients with Type 2 Diabetes Mellitus 
 조민호  ;  정한영  ;  이현철  ;  김경래  ;  임승길  ;  차봉수  ;  안철우  ;  강은석  ;  박종숙  ;  김혜진  ;  남지선  ;  윤지은 
 Clinical Diabetes (임상당뇨병), Vol.8(1S) : 48-56, 2007 
Journal Title
 Clinical Diabetes (임상당뇨병) 
Issue Date
Background: Postprandial glucose level in type 2 diabetes is very important because it has strong correlation with macrovascular complications. Oxidative stress is factor of development and progression of macrovascular complications. The aim of this study is to provide a pharmacologic therapy meeting the means for reducing the risk for macrovascular complications. Materials and Methods: Total 60 type 2 diabetic patients were divided nateglinide group and control group. After 12 weeks, changes of postprandial glucose and oxidative stress were evaluated. Results: Compared with controls, the nateglinide administration group had significant postprandial glucose lowering, and reduced MDA (malondialdehyde) absorption levels. Conclusion: Nateglinide administration for type 2 diabetes, give a possibility of prevention macrovascular complication by lowering postprandial glucose and oxidative stress.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eun Seok(강은석) ORCID logo https://orcid.org/0000-0002-0364-4675
Kim, Kyung Rae(김경래)
Kim, Hae Jin(김혜진)
Nam, Ji Sun(남지선) ORCID logo https://orcid.org/0000-0001-8655-5258
Park, Jong Suk(박종숙) ORCID logo https://orcid.org/0000-0002-5385-1373
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cho, Min Ho(조민호)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
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