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Value of Echo-Doppler Derived Pulmonary Vascular Resistance, Net-Atrioventricular Compliance and Tricuspid Annular Velocity in Determining Exercise Capacity in Patients With Mitral Stenosis

 Eui-Young Choi  ;  Jaemin Shim  ;  Namsik Chung  ;  Yangsoo Jang  ;  Se-Joong Rim  ;  Jong-Won Ha  ;  Donghoon Choi  ;  Seok-Min Kang  ;  Se-Jung Yoon  ;  Chi Young Shim  ;  Sung-Ai Kim 
 CIRCULATION JOURNAL, Vol.71(11) : 1721-1727, 2007 
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Background The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVRecho), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). Methods and Results Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVRecho, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVRecho (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in %VO2 peak. The predictive accuracy for %VO2 peak could increase by combining these parameters as Sa/PVRecho (r=0.500, p=0.004) or Cn· (Sa/PVRecho) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. Conclusions Measurement of PVRecho, Cn and Sa might provide important information about the exercise capacity of patients with MS.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
Kim, Sung Ai(김성애)
Shim, Jae Min(심재민)
Shim, Chi Young(심지영) ORCID logo https://orcid.org/0000-0002-6136-0136
Yoon, Se Jung(윤세정)
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Choi, Eui Young(최의영) ORCID logo https://orcid.org/0000-0003-3732-0190
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
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