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Long-term intraocular pressure fluctuation and progressive visual field deterioration in patients with glaucoma and low intraocular pressures after a triple procedure

 Samin Hong  ;  Gong Je Seong  ;  Young Jae Hong 
 ARCHIVES OF OPHTHALMOLOGY , Vol.125(8) : 1010-1013, 2007 
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OBJECTIVE: To evaluate the association of long-term intraocular pressure (IOP) fluctuation and visual field (VF) progression in patients with glaucoma and low IOP. METHODS: Four hundred eight eyes with IOPs below 18 mm Hg after a triple procedure (phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy) were included in this study. Measurements of IOP and VF were taken for at least 3 years after surgery. Based on the SD in postoperative IOPs, the sample was split into 2 groups (group 1: SD<or=2; group 2: SD>2). Change in VF at each test location was defined as a change in threshold sensitivity of 1 dB per year or higher, with P<or=.01; pointwise linear regression analysis was applied. MAIN OUTCOME MEASURES: Intraocular pressure and VF progression. RESULTS: The groups showed no differences in IOPs through the follow-up period and in the VF defect score 3 months after surgery. After 13 years, more patients with progressive VF deterioration were detected in group 2 than in group 1. CONCLUSION: Our results showed that larger long-term IOP fluctuation was associated with a progressive increase in the VF deterioration even though patients with glaucoma maintained their IOPs after the triple procedure. APPLICATION TO CLINICAL PRACTICE: The SD of long-term IOP should be less than 2 in patients with glaucoma, even if their IOPs drop below 18 mm Hg.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
Hong, Sa Min(홍사민)
Hong, Young Jae(홍영재)
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