Cited 37 times in
Fat-Containing Nodules in the Cirrhotic Liver: Chemical Shift MRI Features and Clinical Implications
DC Field | Value | Language |
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dc.contributor.author | 김기황 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 유정식 | - |
dc.contributor.author | 정재준 | - |
dc.date.accessioned | 2014-12-21T16:22:27Z | - |
dc.date.available | 2014-12-21T16:22:27Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0361-803X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95571 | - |
dc.description.abstract | OBJECTIVE: The purpose of this study was to determine the ability of MRI to predict malignancy in fat-containing nodules in the cirrhotic liver. MATERIALS AND METHODS: In 38 patients with cirrhotic livers, focal lesions > or = 5 mm containing fatty components were identified on chemical shift gradient-echo MRI. Positive predictive values (PPVs) for benignity and malignancy were calculated on the basis of lesion size, T1-weighted hypointensity, T2-weighted hyperintensity, and arterial hypervascularity on the initial MR images. The number of the fatty nodules (group A, up to 4; group B, numerous) in individual patients was also correlated with the malignant potential of the lesions that were verified pathologically or by follow-up imaging studies. RESULTS: In 31 group A patients, 21 (47%) of the 45 lesions showed a malignant course, and their mean diameter (18.8 mm) was larger (p = 0.007) than that (10.5 mm) of benign lesions. In seven group B patients, all 35 lesions (the five largest lesions in each patient; mean diameter, 7.8 mm) proved to be benign. The PPV of larger (> or = 15 mm) fat-containing nodules for malignancy was 85% (11/13 lesions). Six (55%) of 11 immediately diagnosed hepatocellular carcinomas were entirely hypointense on unenhanced in-phase T1-weighted images. The PPV of T2-weighted hyperintensity and arterial hypervascularity for the diagnosis of malignancy was 100% in group A patients. CONCLUSION: In the cirrhotic liver, large size (> or = 15 mm) and T1-weighted hypointensity on in-phase images strongly suggest malignancy of the fat-containing nodules. The presence of numerous nodules < 1 cm suggests that the lesions are benign. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1009~1016 | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF ROENTGENOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Fat-Containing Nodules in the Cirrhotic Liver: Chemical Shift MRI Features and Clinical Implications | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Jeong-Sik Yu | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.identifier.doi | 10.2214/AJR.06.0756 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A02500 | - |
dc.contributor.localId | A03712 | - |
dc.relation.journalcode | J00116 | - |
dc.identifier.eissn | 1546-3141 | - |
dc.identifier.url | http://www.ajronline.org/doi/abs/10.2214/AJR.06.0756 | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | Yu, Jeong Sik | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Yu, Jeong Sik | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 188 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1009 | - |
dc.citation.endPage | 1016 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF ROENTGENOLOGY, Vol.188(4) : 1009-1016, 2007 | - |
dc.identifier.rimsid | 43342 | - |
dc.type.rims | ART | - |
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