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단일기관 내 소아에서 Acinetobacter baumannii 의 감염현황의 분석

Other Titles
 Current Analysis of Acintobacter baumannii Infection among Pediatric Patients in a Single-centered Study 
Authors
 Hye Jin Park ; Jung Min Kim ; Dong Soo Kim ; Ki Hwan Kim 
Citation
 Korean Journal of Pediatric Infectious Diseases (소아감염), Vol.18(1) : 23~30, 2011 
Journal Title
 Korean Journal of Pediatric Infectious Diseases (소아감염) 
ISSN
 1226-3923 
Issue Date
2011
Abstract
Purpose : Acinetobacter baumannii is an aerobic, gram negative coccobacillus. Due to its pathogenicity and ability to accumulate diverse mechanisms of resistance, the importance of this organism is increasing. Many reports have targeted adults, and studies of pediatric patients are limited. This study aims to investigate the current status of A. baumannii infection in children. Methods : From January 2001 to December 2008, 505 patients hospitalized with A. baumannii infection were enrolled. Admission records for underlying disease, duration of hospitalization, previous antibiotic use, location of admission, presence of ventilator care, and resistance to antibiotics were retrospectively reviewed and analyzed. Results : Hemato-oncological disease and neurological disease were 30.6% and 24.3% of all cases; therefore, these were the most common underlying diseases of patients with A. baumannii infection. Prevalence of A. baumannii infection was 78.1% in patients with previous antibiotic use, which was higher than that of the group not using previous antibiotic. And prevalence of multi-drug resistant and pan-drug resistant A. baumannii infection was 76.4% and 38.3% in patients with ICU care, 76.8% and 38.9% with ventilator care, and these were higher than the others. Rate of resistance to all groups of antibiotics showed a gradual increase to over 50% in 2008. Multi-drug resistant A. baumannii was 63.5% and pan-drug resistant A. baumannii was 48.2% of all cases. Conclusion : Prevalence of A. baumannii infection and resistance to antibacterial agents of A. baumannii is increasing. Adequate use of antibiotics and infection control should be emphasized in pediatric patients
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/95163
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pediatrics
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