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Prominent decrease of superior midperipheral endothelial cell density after iris-fixated phakic intraocular lens implantation.

Authors
 Jae Hoon Kim  ;  Bong Joon Choi  ;  Hyunseok Roh  ;  Eung Kweon Kim  ;  Tae-im Kim 
Citation
 JOURNAL OF REFRACTIVE SURGERY, Vol.27(12) : 881-886, 2011 
Journal Title
JOURNAL OF REFRACTIVE SURGERY
ISSN
 1081-597X 
Issue Date
2011
MeSH
Adult ; Cell Count ; Corneal Endothelial Cell Loss/diagnosis ; Corneal Endothelial Cell Loss/etiology* ; Endothelium, Corneal/pathology* ; Female ; Humans ; Iris/surgery ; Lens Implantation, Intraocular/adverse effects* ; Male ; Myopia/surgery ; Phakic Intraocular Lenses* ; Photography ; Suture Techniques ; Young Adult
Abstract
PURPOSE: To evaluate changes in endothelial cell density (ECD) in the corneal region after implantation of an iris-fixated phakic intraocular lens (PIOL).

METHODS: Forty-five eyes of 25 myopic patients implanted with Artisan iris-fixated PIOLs (Ophtec BV) and 30 eyes of 15 myopic controls were enrolled. Corneal ECD and the distance between endothelium and the PIOL optic were evaluated in five different regions (central, nasal, superior, temporal, and inferior) using noncontact specular microscopy and rotating Scheimpflug imaging.

RESULTS: In PIOL-implanted patients, significant differences between the ECD in the superior region, compared with the lowest ECD in any region, and the ECD of the central region, compared with that of the region with highest ECD, were evident. When PIOL-implanted eyes were divided based on time since operation, a significant difference was observed only in patients for whom at least 48 postoperative months had elapsed. In untreated myopic controls, the greatest ECD was observed at the superior cornea. The distance between the central corneal endothelium and PIOL was significantly longer than that of the peripheral locations.

CONCLUSIONS: The extent of ECD decrease was not consistent throughout the cornea after implantation of an iris-fixated PIOL. Therefore, ECD measurement not only at the corneal center but also at midperipheral corneal locations, especially in the superior cornea, may be important in patients with irisfixated PIOLs.
Full Text
http://www.healio.com/ophthalmology/journals/jrs/%7Ba54bfed6-0185-447e-952c-bd5113b37bad%7D/prominent-decrease-of-superior-midperipheral-endothelial-cell-density-after-iris-fixated-phakic-intraocular-lens-implantation
DOI
10.3928/1081597X-20110802-03
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Jae Hun(김재훈)
Kim, Tae-Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94792
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