Cited 238 times in

Prevalence of primary open-angle glaucoma in central South Korea the Namil study

Authors
 Chang-sik Kim  ;  Gong Je Seong  ;  Nam-ho Lee  ;  Ki-chul Song  ;  Namil Study Group  ;  Korean Glaucoma Society 
Citation
 OPHTHALMOLOGY, Vol.118(6) : 1024-1030, 2011 
Journal Title
OPHTHALMOLOGY
ISSN
 0161-6420 
Issue Date
2011
MeSH
Adult ; Age Distribution ; Aged ; Cross-Sectional Studies ; Female ; Glaucoma, Open-Angle/epidemiology* ; Humans ; Male ; Middle Aged ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; Rural Population* ; Vision Screening/methods
Abstract
PURPOSE: To assess the prevalence of primary open-angle glaucoma (POAG) in the Namil-myon area in central South Korea.

DESIGN: A cross-sectional, epidemiologic study in a defined population.

PARTICIPANTS: Residents aged ≥ 40 years in Namil-myon, a rural agricultural area in central South Korea.

METHODS: Each subject underwent a screening that consisted of an interview and ophthalmic examinations, including visual acuity measurement, autorefraction, anterior segment evaluation by optical biometry, slit-lamp examination, Goldmann applanation tonometry, binocular optic disc evaluation, fundus photography, pachymetry, gonioscopy, and screening visual field test using frequency doubling technology. Subjects with suspected glaucoma were referred for definitive examinations. Standard automated field tests and retinal nerve fiber layer analysis using optical coherence tomography (Stratus OCT) or scanning laser polarimetry (GDx VCC) were performed. A diagnosis of glaucoma was made based on the optic disc shape, retinal nerve fiber layer appearance, perimetric results, and other ocular findings.

MAIN OUTCOME MEASURES: Prevalence of POAG, mean intraocular pressure (IOP), and mean central corneal thickness (CCT).

RESULTS: Of 1928 eligible residents in the area, 1532 (79.5%) participated in this study. The estimated prevalence of POAG in the population aged ≥ 40 years was 3.5% (95% confidence interval [CI], 2.7%-4.3%). The prevalence of POAG with an IOP of ≤ 21 mmHg was 2.7% (95% CI, 2.1%-3.3%), and the prevalence of POAG with an IOP of ≥ 22 mmHg was 0.8% (95% CI, 0.4%-1.2%). The mean IOP for POAG eyes (16.3 ± 4.6 mmHg) was significantly higher than nonglaucomatous eyes (13.3 ± 2.7 mmHg; P = .001). The mean CCT of POAG eyes with an IOP of ≤ 21 mmHg was 528 ± 26 μm, and that of POAG eyes with an IOP ≥ 22 mmHg was 531 ± 37 μm; these values were not significantly different from that of nonglaucomatous eyes (530 ± 31 μm; P = .943 and .996, respectively).

CONCLUSIONS: The prevalences of POAG and POAG with an IOP ≤ 21 mmHg in the Namil-myon region of central South Korea were higher than that in most previous reports worldwide, but were similar to the reported rates in black and Japanese populations. The mean IOP of POAG eyes was higher than nonglaucomatous eyes, but the mean CCTs were not different.

FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any of the materials discussed in this article.
Full Text
http://www.sciencedirect.com/science/article/pii/S0161642010010900
DOI
10.1016/j.ophtha.2010.10.016
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94408
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links