Cited 21 times in
Hypervascular hepatocellular carcinoma in the cirrhotic liver: diffusion-weighted imaging versus superparamagnetic iron oxide-enhanced MRI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기황 | - |
dc.contributor.author | 김대중 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 유정식 | - |
dc.contributor.author | 정재준 | - |
dc.contributor.author | 정진 | - |
dc.date.accessioned | 2014-12-20T17:12:55Z | - |
dc.date.available | 2014-12-20T17:12:55Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0730-725X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94174 | - |
dc.description.abstract | PURPOSE: The purpose of the study was to validate diffusion-weighted imaging (DWI) in the assessment of hypervascular hepatocellular carcinoma (HCC) compared with superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI) in the cirrhotic liver. MATERIAL AND METHODS: Forty-six consecutive patients with 106 hypervascular focal lesions in the cirrhotic liver who underwent DWI using three b factors and gadopentetate dimeglumine-enhanced dynamic MRI followed by SPIO-enhanced MRI were enrolled. Two independent radiologists evaluated two separated image sets (SPIO set, dynamic MRI and SPIO-enhanced T2*-weighted images; DWI set, DWI and dynamic MRI) and assigned confidence levels for diagnosis of HCC using a five-point scale for each lesion. Area under the receiver operating characteristic curve (A(z)) was calculated for each image set. RESULTS: The A(z) value of the DWI set was larger than the SPIO set by both readers (reader 1, 0.936 vs. 0.900, P=.050; reader 2, 0.938 vs. 0.905, P=.110). For the sensitivity (reader 1, 93.1% vs. 86.2%, P=.146; reader 2, 95.4% vs. 88.5%, P=.070) and specificity (reader 1, 89.5% vs. 73.7%, P=.250; reader 2, 79.0% vs. 73.7%, P=1.000) of HCC diagnosis, DWI sets were superior to SPIO sets without statistically significant differences. CONCLUSION: For assessment of hypervascular HCC, DWI in combination with dynamic MRI provides comparable or slightly better information compared with the combination of dynamic and SPIO-enhanced MRI | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1235~1243 | - |
dc.relation.isPartOf | MAGNETIC RESONANCE IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Carcinoma,Hepatocellular/pathology* | - |
dc.subject.MESH | Contrast Media/pharmacology | - |
dc.subject.MESH | Diffusion Magnetic ResonanceImaging/methods | - |
dc.subject.MESH | Ferric Compounds/pharmacology* | - |
dc.subject.MESH | Fibrosis/virology | - |
dc.subject.MESH | Gadolinium DTPA/pharmacology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver/pathology | - |
dc.subject.MESH | LiverCirrhosis/pathology* | - |
dc.subject.MESH | LiverNeoplasms/pathology* | - |
dc.subject.MESH | Magnetic ResonanceImaging/methods* | - |
dc.subject.MESH | Observer Variation | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Radiology/methods | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Hypervascular hepatocellular carcinoma in the cirrhotic liver: diffusion-weighted imaging versus superparamagnetic iron oxide-enhanced MRI | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Jin Chung | - |
dc.contributor.googleauthor | Jeong-Sik Yu | - |
dc.contributor.googleauthor | Dae Jung Kim | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 10.1016/j.mri.2011.07.025 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A00369 | - |
dc.contributor.localId | A02500 | - |
dc.contributor.localId | A03712 | - |
dc.contributor.localId | A03740 | - |
dc.relation.journalcode | J02178 | - |
dc.identifier.eissn | 1873-5894 | - |
dc.identifier.pmid | 21907517 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0730725X11002888 | - |
dc.subject.keyword | Liver | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | Diffusion | - |
dc.subject.keyword | Magnetic resonance | - |
dc.subject.keyword | Superparamagnetic iron oxide (SPIO) | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Dae Jung | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | Yu, Jeong Sik | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.alternativeName | Chung, Jin | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Kim, Dae Jung | - |
dc.contributor.affiliatedAuthor | Yu, Jeong Sik | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Chung, Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 29 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1235 | - |
dc.citation.endPage | 1243 | - |
dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IMAGING, Vol.29(9) : 1235-1243, 2011 | - |
dc.identifier.rimsid | 27288 | - |
dc.type.rims | ART | - |
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