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다제내성 결핵환자에서 Prothionamide에 의한 급성 간염 1예

Other Titles
 A Case of Prothionamide Induced Hepatitis on Patient with Multi-Drug Resistant Pulmonary Tuberculos 
Authors
 박준범  ;  박병훈  ;  손지영  ;  정지예  ;  김은영  ;  임주은  ;  이상훈  ;  이상국  ;  김송이  ;  정원재  ;  임승택  ;  이경종  ;  강영애  ;  김영삼  ;  김세규  ;  장 준  ;  최준정  ;  박무석 
Citation
 Tuberculosis and Respiratory Diseases, Vol.70(3) : 251-256, 2011 
Journal Title
 Tuberculosis and Respiratory Diseases 
ISSN
 1738-3536 
Issue Date
2011
Abstract
The prevalence of multi-drug resistant tuberculosis (MDR-TB), which is resistant to isoniazid and rifampin, has been increasing in Korea. And the side effects of 2nd line anti-tuberculosis medications, including drug-induced hepatitis, are well known. Although prothionamide (PTH) is one of the most useful anti-TB medications and although TB medication-induced acute hepatitis is a severe complication, there are only a few published case reports about prothionamide induced hepatitis. In this case report, a 22 year old male was diagnosed with pulmonary MDR-TB and was administered 2nd line anti-TB mediations, including PTH. Afterwards, he had a spiking fever and his liver enzymes were more than 5 times greater than the upper limit of the normal range. He was then diagnosed with drug-induced hepatitis by liver biopsy. His symptoms and liver enzyme elevation were improved after stopping PTH. Accordingly, we report this case of an association between PTH and acute hepatitis
Files in This Item:
T201103146.pdf Download
DOI
10.4046/trd.2011.70.3.251
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
강영애(Kang, Young Ae) ORCID logo https://orcid.org/0000-0002-7783-5271
김세규(Kim, Se Kyu)
김송이(Kim, Song Yee) ORCID logo https://orcid.org/0000-0001-8627-486X
김영삼(Kim, Young Sam) ORCID logo https://orcid.org/0000-0001-9656-8482
김은영(Kim, Eun Young) ORCID logo https://orcid.org/0000-0002-3281-5744
박무석(Park, Moo Suk) ORCID logo https://orcid.org/0000-0003-0820-7615
박병훈(Park, Byung Hoon)
박준범(Park, Jun Beom)
손지영(Son, Ji Young)
이경종(Lee, Kyung Jong)
이상국(Lee, Sang Kook)
이상훈(Lee, Sang Hoon) ORCID logo https://orcid.org/0000-0002-7706-5318
임승택(Lim, Seung Taek)
임주은(Lim, Ju Eun)
장준(Chang, Joon)
정원재(Jung, Won Jai)
정지예(Jung, Ji Ye) ORCID logo https://orcid.org/0000-0003-1589-4142
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93965
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