Cited 1 times in

소화기질환에서 줄기세포 치료의 현재와 미래 ; 소화기질환에서의 줄기세포를 이용한 임상연구와 줄기세포 치료의 미래

Other Titles
 Clinical Trials with Stem Cells in Digestive Diseases and Future Perspectives 
Authors
 Tae Il Kim 
Citation
 Korean Journal of Gastroenterology, Vol.58(3) : 139-143, 2011 
Journal Title
Korean Journal of Gastroenterology
ISSN
 1598-9992 
Issue Date
2011
MeSH
Bone Marrow Cells/cytology ; Clinical Trials as Topic ; Crohn Disease/therapy ; Digestive System Diseases/therapy* ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/cytology ; Humans ; Liver Cirrhosis/therapy ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stromal Cells/cytology
Keywords
Stem cell ; Clinical trial ; Digestive system disease ; Crohn`s disease ; Liver cirrhosis
Abstract
Many techniques for isolation, expansion and handling of stem cells are being developed rapidly, and preclinical evidence has shown the possibility to use this technology for refractory diseases in the near future. Among refractory digestive diseases, Crohn`s disease and liver cirrhosis may be two main diseases where stem cell therapy can be applied for anti-inflammation and regeneration of tissue. Currently, with respect to these two diseases, clinical trials using hematopoietic stem cells and mesenchymal stem cells from bone marrow or adipose tissue have shown some evidence of clinical benefits to immune modulation, suppression of inflammation and regeneration of functional cells. However, for the development of practical stem cell therapy, we need more data on underlying mechanisms, effective subpopulation of stem cells and its sources, and effective parameters for monitoring and estimation. With technical advances, the research on embryonic and induced pluripotent stem cells will also contribute to the new therapeutic strategies for digestive regenerative medicine. In the future, a variety of stem cell therapies may be therapeutic options for refractory digestive diseases, but many technical challenges remain to be solved
Full Text
http://kiss.kstudy.com/journal/thesis_name.asp?tname=kiss2002&key=2944377
DOI
10.4166/kjg.2011.58.3.139
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Tae Il(김태일) ORCID logo https://orcid.org/0000-0003-4807-890X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93951
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links