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소화기질환에서 줄기세포 치료의 현재와 미래 ; 소화기질환에서의 줄기세포를 이용한 임상연구와 줄기세포 치료의 미래

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dc.contributor.author김태일-
dc.date.accessioned2014-12-20T17:05:41Z-
dc.date.available2014-12-20T17:05:41Z-
dc.date.issued2011-
dc.identifier.issn1598-9992-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93951-
dc.description.abstractMany techniques for isolation, expansion and handling of stem cells are being developed rapidly, and preclinical evidence has shown the possibility to use this technology for refractory diseases in the near future. Among refractory digestive diseases, Crohn`s disease and liver cirrhosis may be two main diseases where stem cell therapy can be applied for anti-inflammation and regeneration of tissue. Currently, with respect to these two diseases, clinical trials using hematopoietic stem cells and mesenchymal stem cells from bone marrow or adipose tissue have shown some evidence of clinical benefits to immune modulation, suppression of inflammation and regeneration of functional cells. However, for the development of practical stem cell therapy, we need more data on underlying mechanisms, effective subpopulation of stem cells and its sources, and effective parameters for monitoring and estimation. With technical advances, the research on embryonic and induced pluripotent stem cells will also contribute to the new therapeutic strategies for digestive regenerative medicine. In the future, a variety of stem cell therapies may be therapeutic options for refractory digestive diseases, but many technical challenges remain to be solved-
dc.description.statementOfResponsibilityopen-
dc.format.extent139~143-
dc.relation.isPartOfKorean Journal of Gastroenterology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBone Marrow Cells/cytology-
dc.subject.MESHClinical Trials as Topic-
dc.subject.MESHCrohn Disease/therapy-
dc.subject.MESHDigestive System Diseases/therapy*-
dc.subject.MESHHematopoietic Stem Cell Transplantation-
dc.subject.MESHHematopoietic Stem Cells/cytology-
dc.subject.MESHHumans-
dc.subject.MESHLiver Cirrhosis/therapy-
dc.subject.MESHMesenchymal Stem Cell Transplantation-
dc.subject.MESHMesenchymal Stromal Cells/cytology-
dc.title소화기질환에서 줄기세포 치료의 현재와 미래 ; 소화기질환에서의 줄기세포를 이용한 임상연구와 줄기세포 치료의 미래-
dc.title.alternativeClinical Trials with Stem Cells in Digestive Diseases and Future Perspectives-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorTae Il Kim-
dc.identifier.doi10.4166/kjg.2011.58.3.139-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01079-
dc.relation.journalcodeJ02014-
dc.identifier.pmid21960101-
dc.identifier.urlhttp://kiss.kstudy.com/journal/thesis_name.asp?tname=kiss2002&key=2944377-
dc.subject.keywordStem cell-
dc.subject.keywordClinical trial-
dc.subject.keywordDigestive system disease-
dc.subject.keywordCrohn`s disease-
dc.subject.keywordLiver cirrhosis-
dc.contributor.alternativeNameKim, Tae Il-
dc.contributor.affiliatedAuthorKim, Tae Il-
dc.rights.accessRightsnot free-
dc.citation.volume58-
dc.citation.number3-
dc.citation.startPage139-
dc.citation.endPage143-
dc.identifier.bibliographicCitationKorean Journal of Gastroenterology, Vol.58(3) : 139-143, 2011-
dc.identifier.rimsid28571-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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