NMO-IgG 양성 환자에서 숨뇌 병변에 의하여 발생된 난치성 구토 1예

Abstract

NMO-IgG is highly specific for neuromyelitis optica and reacts with the water channel aquaporin 4, which expressed particularly in the periventricular and periaqueductal areas, including dorsomedial regions of the medulla oblongata, where emetic circuitry may exist. We report an intractable vomiting in a NMO-IgG positive patient. She suffered from recurrent myelitis. Brain MRI revealed a single focal T2 high signal intensity in the area postrema or nucleus tractus solitaries. Intractable vomiting may be caused by neuromyelitis optica spectrum disorder.