Cited 125 times in
Outcomes and prognostic factors of intracranial unruptured vertebrobasilar artery dissection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김동익 | - |
dc.contributor.author | 김동준 | - |
dc.contributor.author | 김병문 | - |
dc.contributor.author | 박근영 | - |
dc.contributor.author | 박성일 | - |
dc.contributor.author | 서상현 | - |
dc.contributor.author | 안성수 | - |
dc.date.accessioned | 2014-12-20T16:44:44Z | - |
dc.date.available | 2014-12-20T16:44:44Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0028-3878 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93297 | - |
dc.description.abstract | OBJECTIVE: We aimed to evaluate the long-term clinical outcomes and prognostic factors of symptomatic intracranial unruptured vertebrobasilar artery dissection (siu-VBD). METHODS: A total of 191 patients (M:F = 127:64; median age, 46 years) with siu-VBD were treated between January 2001 and December 2008. Presentations, treatments, outcomes, and prognostic factors were retrospectively analyzed. RESULTS: Clinical manifestations were ischemic symptoms with headache (n = 97) or without headache (n = 13) and headache without ischemic symptoms (n = 81). Forty-six patients (24.1%) underwent endovascular treatment. The remaining 145 patients (75.9%) were medically treated with anticoagulants (n = 49), antiplatelets (n = 48), or analgesics alone (n = 48). Clinical follow-up data were available in 178 patients (102 ischemic and 76 nonischemic) at 15 to 102 months (mean, 46 months). None of the siu-VBD hemorrhaged. All 76 patients without ischemic presentation had favorable outcomes (modified Rankin Scale, 0-1). Of the 102 patients with ischemic presentation, outcomes were favorable in 92 and unfavorable in 10 patients. Four patients died; 3 died of causes unrelated to VBD, and one died as a result of basilar artery (BA) dissection. Old age (odds ratio [OR] 1.099; 95% confidence interval [CI] 1.103-1.204; p = 0.042) and BA involvement (OR 11.886; 95% CI 1.416-99.794; p = 0.023) were independent predictors of unfavorable outcomes in siu-VBD with ischemic presentation. CONCLUSIONS: Clinical outcomes for siu-VBD were favorable in all patients without ischemic symptoms and in most patients with ischemic presentation. None of the siu-VBD caused subarachnoid hemorrhage. Old age and BA involvement were independent predictors of unfavorable outcome in siu-VBD with ischemic presentation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1735~1741 | - |
dc.relation.isPartOf | NEUROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Analgesics/therapeutic use | - |
dc.subject.MESH | Anticoagulants/therapeutic use | - |
dc.subject.MESH | Cerebral Angiography | - |
dc.subject.MESH | Diffusion Magnetic Resonance Imaging | - |
dc.subject.MESH | Endovascular Procedures | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Processing, Computer-Assisted | - |
dc.subject.MESH | Intracranial Aneurysm/diagnosis | - |
dc.subject.MESH | Intracranial Aneurysm/surgery | - |
dc.subject.MESH | Intracranial Aneurysm/therapy* | - |
dc.subject.MESH | Magnetic Resonance Angiography | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Platelet Aggregation Inhibitors/therapeutic use | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Vertebral Artery Dissection/diagnosis | - |
dc.subject.MESH | Vertebral Artery Dissection/surgery | - |
dc.subject.MESH | Vertebral Artery Dissection/therapy* | - |
dc.subject.MESH | Vertebrobasilar Insufficiency/diagnosis | - |
dc.subject.MESH | Vertebrobasilar Insufficiency/surgery | - |
dc.subject.MESH | Vertebrobasilar Insufficiency/therapy* | - |
dc.title | Outcomes and prognostic factors of intracranial unruptured vertebrobasilar artery dissection | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | B.M. Kim | - |
dc.contributor.googleauthor | S.H. Kim | - |
dc.contributor.googleauthor | D.I. Kim | - |
dc.contributor.googleauthor | Y.S. Shin | - |
dc.contributor.googleauthor | S.H. Suh | - |
dc.contributor.googleauthor | D.J. Kim | - |
dc.contributor.googleauthor | S.I. Park | - |
dc.contributor.googleauthor | K.Y. Park | - |
dc.contributor.googleauthor | S.S. Ahn | - |
dc.identifier.doi | 10.1212/WNL.0b013e31821a7d94 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02234 | - |
dc.contributor.localId | A00408 | - |
dc.contributor.localId | A00410 | - |
dc.contributor.localId | A00498 | - |
dc.contributor.localId | A01510 | - |
dc.contributor.localId | A01886 | - |
dc.contributor.localId | A01442 | - |
dc.relation.journalcode | J02340 | - |
dc.identifier.eissn | 1526-632X | - |
dc.identifier.pmid | 21576691 | - |
dc.identifier.url | http://www.neurology.org/content/76/20/1735.long | - |
dc.contributor.alternativeName | Kim, Dong Ik | - |
dc.contributor.alternativeName | Kim, Dong Joon | - |
dc.contributor.alternativeName | Kim, Byung Moon | - |
dc.contributor.alternativeName | Park, Keun Young | - |
dc.contributor.alternativeName | Park, Sung Il | - |
dc.contributor.alternativeName | Suh, Sang Hyun | - |
dc.contributor.alternativeName | Ahn, Sung Soo | - |
dc.contributor.affiliatedAuthor | Ahn, Sung Soo | - |
dc.contributor.affiliatedAuthor | Kim, Dong Ik | - |
dc.contributor.affiliatedAuthor | Kim, Dong Joon | - |
dc.contributor.affiliatedAuthor | Kim, Byung Moon | - |
dc.contributor.affiliatedAuthor | Park, Sung Il | - |
dc.contributor.affiliatedAuthor | Suh, Sang Hyun | - |
dc.contributor.affiliatedAuthor | Park, Keun Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 76 | - |
dc.citation.number | 20 | - |
dc.citation.startPage | 1735 | - |
dc.citation.endPage | 1741 | - |
dc.identifier.bibliographicCitation | NEUROLOGY, Vol.76(20) : 1735-1741, 2011 | - |
dc.identifier.rimsid | 27118 | - |
dc.type.rims | ART | - |
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