7 439

Cited 52 times in

Comparison of laparoscopic versus open radical nephrectomy for large renal tumors: a retrospective analysis of multi-center results.

 Seung Hyun Jeon  ;  Tae Gyun Kwon  ;  Koon Ho Rha  ;  Gyung Tak Sung  ;  Wan Lee  ;  Jae Sung Lim  ;  Young Beom Jeong  ;  Sung Hoo Hong  ;  Hyeon Hoe Kim  ;  Seok-Soo Byun 
 BJU INTERNATIONAL, Vol.107(5) : 817-821, 2011 
Journal Title
Issue Date
Adult ; Aged ; Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/surgery* ; Epidemiologic Methods ; Female ; Humans ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery* ; Laparoscopy* ; Male ; Middle Aged ; Nephrectomy/adverse effects ; Nephrectomy/methods* ; Postoperative Complications/etiology ; Treatment Outcome ; Tumor Burden
renal cell carcinoma ; laparoscopic radical nephrectomy ; minimally invasive surgery.
OBJECTIVE: • To assess the feasibility and oncologic efficacy of laparoscopic radical nephrectomy (LRN) compared with open radical nephrectomy (ORN) in patients with large renal cell carcinomas (RCCs) > 7 cm in size.

PATIENTS AND METHODS: • We analysed the data from 255 patients who underwent radical nephrectomies at 26 institutions in Korea between January 2000 and December 2007 for RCCs > 7 cm in size. • Eighty-eight patients who underwent LRNs were compared with 167 patients who underwent ORNs. The patients with tumor thrombi in the renal vein or IVC, and lymph node or distant metastases were excluded. • We compared the operative time, estimated blood loss, complication rates, and 2-year overall and disease-free survival rates between the LRN and ORN groups.

RESULTS: • The median duration of postoperative follow-up was 19 months for the LRN group and 25.8 months for the ORN group. • The operative time was significantly longer in the LRN group than in the ORN group (241.5 ± 74.8 min vs 202.7 ± 69.6 min, P < 0.001) and blood loss was significantly lower in the LRN group than in the ORN group (439.8 ± 326.8 mL vs 604.4 ± 531.4 mL, P = 0.006). • No statistically significant difference was found in complication rates, the 2-year overall (92.7% vs 94%, P = 0.586) and disease-specific (90.1% vs 93.7%, P = 0.314) survival rates between the LRN and ORN groups.

CONCLUSIONS: • Despite the longer operative time, LRN was an effective
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Rha, Koon Ho(나군호) ORCID logo https://orcid.org/0000-0001-8588-7584
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.