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A comparison of predictability of cardiovascular events between each metabolic component in patients with metabolic syndrome based on the revised National Cholesterol Education Program criteria.

 In-Cheol Hwang  ;  Kyoung-Kon Kim  ;  Sun-Ha Jee  ;  Hee-Cheol Kang 
 YONSEI MEDICAL JOURNAL, Vol.52(2) : 220-226, 2011 
Journal Title
Issue Date
Age Factors ; Blood Glucose/analysis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology* ; Chi-Square Distribution ; Female ; Health Promotion ; Health Surveys ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Male ; Metabolic Syndrome/complications ; Metabolic Syndrome/diagnosis* ; Metabolic Syndrome/epidemiology ; Middle Aged ; Odds Ratio ; Republic of Korea/epidemiology ; Risk Factors ; Sex Factors
Metabolic components ; cardiovascular disease ; fasting glucose
PURPOSE: The prevalence of metabolic syndrome (MetS) generally varies depending on its diagnostic definition, and many different definitions inevitably lead to substantial confusion and lack of comparability between studies. Despite extensive research, there is still no gold standard for the definition of MetS, which continues to be a matter of debate. In this study, we investigate whether and to what extent its individual components are related to the risk of cardiovascular disease (CVD) in Korean population.

MATERIALS AND METHODS: We used data from the 2005 Korea National Health and Nutrition Examination Survey, which is a nationally representative survey of the noninstitutionalized civilian population. The study sample consisted of 1,406 Korean adults (587 men, 819 women) who were diagnosed with MetS based on the revised National Cholesterol Education Program (NCEP) criteria. Central obesity is defined as a waist circumference cutoff point reported in Asia-Pacific criteria for obesity based on waist circumference by the World Health Organization. CVD was defined as presence of stroke, myocardial infarction, or angina pectoris on a medical history questionnaire.

RESULTS: The CVD prevalence among the subjects was 6.8% for men and 8.6% for women. Besides age, the components of MetS showing a significant difference in the number of CVD events were high fasting glucose (FG) in men and high blood pressure (BP) and high FG in women. After adjusting for gender and age, high FG was shown to yield a significant difference (odds ratio: unadjusted 2.08, adjusted 1.81), alone among all MetS components. However, after adjusting for only age, no significant difference was found.

CONCLUSION: Fasting glucose level is the highest predicting factor for CVD in Korean patients with MetS based on the revised NECP definition
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1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Kang, Hee Cheol(강희철) ORCID logo https://orcid.org/0000-0002-0309-7448
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
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