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Tox-Info 시스템의 중독정보 데이터베이스와 응급실에 내원하는 중독 환자 분포의 비교

Other Titles
 Comparison between Emergency Patient Poisoning Cases and the Tox-Info System Database 
Authors
 김현종  ;  김양원  ;  김현  ;  박창배  ;  소병학  ;  이경룡  ;  이경우  ;  이경원  ;  이성우  ;  이장영  ;  조규종  ;  조준호  ;  정성필 
Citation
 Journal of the Korean Society of Clinical Toxicology (대한임상독성학회지), Vol.10(1) : 8-14, 2012 
Journal Title
 Journal of the Korean Society of Clinical Toxicology  (대한임상독성학회지) 
ISSN
 1738-1320 
Issue Date
2012
Abstract
Purpose: The Tox-Info system is a poisonous substance information database developed by the Korean National Institute of Food and Drug Safety Evaluation. The aim of this study was to estimate the coverage effectiveness of the Tox-Info system by comparing the toxic substances included in the database with the distribution of the toxic substances implicated in the cases of intoxicated patients presenting to emergency departments. The secondary aim of the study was to propose any additional substances that should be added to the database. Methods: We retrospectively reviewed the medical records of patients suffering with toxic exposure who had visited any of 12 selected emergency departments in Korea from January 2010 to December 2011. The identified toxic substances were classified into groups including prescription drugs, agricultural chemicals, household products, animals or plants, herbal drugs, and others. We calculated the coverage rate of the Tox-Info database relative to the number of intoxication cases and the type of toxic substances involved. Results: A total of 5,840 intoxicated patient records were collected. Their mean age was $46.6{\pm}20.5$ years and 56.2% were female. Of the total intoxication cases, 87.8% of the identified toxic substances were included in the Tox-Info database, while only 41.6% of all of the types of identified toxic substances were included. Broken down by category, 122 prescription drugs, 15 agricultural chemicals, 12 household products, 14 animals or plants and 2 herbal drugs involved in poisoning cases were not included in the Tox-info database. Conclusion: This study demonstrated the clinical usefulness of the Tox-Info system. While 87.8% of the substances involved in the cases were included in the Tox-Info database, the database should be continuously updated in order to include even the most uncommon toxic substances.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92330
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실)
Yonsei Authors
김현종(Kim, Hyun Jong) ; 정성필(Chung, Sung Pil)
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