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뇌사자 간이식에서 이식 대기자의 응급도 평가지표로서 KONOS 응급도와 MELD 점수와의 비교

Other Titles
 Severity of End-stage Liver Disease in Liver Transplant Candidate; Comparison of KONOS Status with MELD Score. 
Authors
 주동진 ; 김명수 ; 최진섭 ; 최기홍 ; 허규하 ; 전경옥 ; 김순일 
Citation
 대한이식학회지, Vol.26(2) : 112~119, 2012 
Journal Title
 대한이식학회지 
ISSN
 1598-1711 
Issue Date
2012
Abstract
BACKGROUND: We have allocated liver according to the Korean Network Organ Sharing (KONOS) status. However, it was necessary to change the system to a more adequate and objective system. We analyzed the correlation between KONOS status and MELD score under the current status of organ allocation. METHODS: We reviewed medical records of 70 liver recipients as KONOS status 2A and 2B between September 2005 and December 2010. We analyzed their KONOS status, MELD score, clinical characteristics, waiting time, Child-Turcotte-Pugh (CTP) score and clinical symptoms accorded to KONOS status 2A. RESULTS: Mean MELD and CTP score of the 2A group was significantly higher than the 2B group (P<0.001). In the 2B group, the blood types of all recipients were identical to those of the donors. However, 2A group included 7 cases (23.3%) of non-identical blood types. The MELD score of all recipients were correlated with CTP score (R=0.798, P<0.001). However, there was an overlapping area between the 2B group and the 2A group that was registered by the condition of intractable ascites. Those who had hepatorenal syndrome and hepatic encephalopathy showed high MELD score over 20. However, 36.4% of the patients who had only intractable ascites showed a MELD score of less than 20. CONCLUSIONS: CTP score was highly correlated with MELD score. However, KONOS status showed some overlapping area of the MELD score between 2A and 2B groups. We should make an effort to improve KONOS allocation system to meet the Korean situation.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/92315
DOI
10.4285/jkstn.2012.26.2.112
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
Yonsei Authors
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