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응급센터로 내원한 급성 췌장염 환자에서 경증 임상경과를 예측하기 위해 CTSI와 비교한 Harmless Acute Pancreatitis Score

Other Titles
 Comparative evaluation of the harmless acute pancreatitis score and CT severity index to predict mild clinical course of acute pancreatitis in the emergency department 
Authors
 강성우 ; 이누가 ; 이한식 ; 정성필 ; 유제성 ; 김현종 
Citation
 대한응급의학회지, Vol.23(6) : 841~846, 2012 
Journal Title
 대한응급의학회지 
ISSN
 1226-4334 
Issue Date
2012
Abstract
Purpose: Several scoring systems and biochemical markers have been proposed for the early prediction of acute pancreatitis. The Harmless Acute Pancreatitis Score (HAPS) is a novel scoring system to recognize acute pancreatitis patients with a non-severe clinical course. This study was conducted to evaluate the usefulness of HAPS to predict good prognosis of acute pancreatitis in the emergency department (ED). Methods: We retrospectively reviewed the electronic medical records of patients who presented to the ED with acute pancreatitis from January 2010 to December 2011. The parameters constituting HAPS, including physical signs of peritonitis (rebound abdominal tenderness), hematocrit and serum creatinine levels were abstracted. Severe clinical course was defined as having one of the following: mortality while in hospital, necrosis as assessed by contrast CT, need for artificial ventilation or dialysis. The diagnostic performance of HAPS for predicting harmless course was evaluated by sensitivity, specificity, and predictive values. Results: During the study period, 144 patients with a final diagnosis of acute pancreatitis were included. Among these 144 patients, 79 were predicted to have a non-severe course by HAPS, of whom 4 patients progressed to severe pancreatitis. The sensitivity, specificity, positive and negative predictive values were 61.5%, 81.8%, 94.9% and 27.7%, respectively. Conclusion: This study suggests that HAPS is simple and can be assessed within a few hours in the ED. HAPS also showed a high positive predictive value that predicts a nonsevere course of acute pancreatitis. Therefore, HAPS may be used as a scoring system to identify non-severe acute pancreatitis in the ED.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/92306
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Emergency Medicine
Yonsei Authors
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