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Practice patterns of Korean urologists for screening and managing prostate cancer according to PSA level

Authors
 Mun Su Chung  ;  Seung Hwan Lee  ;  Dong Hoon Lee  ;  Se Joong Kim  ;  Choung Soo Kim  ;  Kyu Sung Lee  ;  Jae Il Jung  ;  Sae Woong Kim  ;  Yil Seob Lee  ;  Byung Ha Chung 
Citation
 YONSEI MEDICAL JOURNAL, Vol.53(6) : 1136-1141, 2012 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2012
MeSH
Aged ; Asian Continental Ancestry Group ; Biopsy ; Humans ; Male ; Middle Aged ; Physicians ; Prostate-Specific Antigen/blood* ; Prostatic Neoplasms/blood* ; Prostatic Neoplasms/diagnosis* ; Retrospective Studies ; Urology
Keywords
Mass screening ; prostate biopsy ; prostate specific antigen
Abstract
PURPOSE: There are still debates on the benefit of mass screening for prostate cancer (PCA) by prostate specific antigen (PSA) testing, and on systemized surveillance protocols according to PSA level. Furthermore, there is a paucity of literature on current practice patterns according to PSA level in the Korean urologic field. Here, we report the results of a nationwide, multicenter, retrospective chart-review study.

MATERIALS AND METHODS: Overall 2122 Korean men (>40 years old, PSA >2.5 ng/mL) were included in our study (from 122 centers, in 2008). The primary endpoint was to analyze the rate of prostate biopsy according to PSA level. Secondary aims were to analyze the detection rate of PCA, the clinical features of patients, and the status of surveillance for PCA according to PSA level.

RESULTS: The rate of prostate biopsy was 7.1%, 26.3%, 54.2%, and 64.3% according to PSA levels of 2.5-3.0, 3.0-4.0, 4.0-10.0, and >10.0 ng/mL, respectively, and the PCA detection rate was 16.0%, 22.2%, 20.2%, and 59.6%, respectively. At a PSA level >4.0 ng/mL, we found a lower incidence of prostate biopsy in local clinics than in general hospitals (21.6% vs. 66.2%, respectively). A significant proportion (16.6%) of patients exhibited high Gleason scores (≥8) even in the group with low PSA values (2.5-4.0 ng/mL).

CONCLUSION: We believe that the results from this nationwide study might provide an important database for the establishment of practical guidelines for the screening and management of PCA in Korean populations.
Files in This Item:
T201203718.pdf Download
DOI
10.3349/ymj.2012.53.6.1136
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Dong Hoon(이동훈)
Lee, Seung Hwan(이승환) ORCID logo https://orcid.org/0000-0001-7358-8544
Chung, Mun Su(정문수)
Chung, Byung Ha(정병하) ORCID logo https://orcid.org/0000-0001-9817-3660
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92152
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