Cited 0 times in
Diffusion-weighted MR imaging before and after contrast enhancement with superparamagnetic iron oxide for assessment of hepatic metastasis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기황 | - |
dc.contributor.author | 김주희 | - |
dc.contributor.author | 김하나 | - |
dc.contributor.author | 유정식 | - |
dc.contributor.author | 정재준 | - |
dc.date.accessioned | 2014-12-19T17:49:34Z | - |
dc.date.available | 2014-12-19T17:49:34Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/92130 | - |
dc.description.abstract | PURPOSE: The purpose of our study was to validate diffusion-weighted MRI (DWI) before and after superparamagnetic iron oxide (SPIO) injection for assessment of hepatic metastases. MATERIALS AND METHODS: Eighty-six hepatic metastases (size range, 0.3-4.7 cm; mean, 1.5 cm) verified pathologically or by follow-up imaging studies in 22 consecutive patients (17 men and 5 women; 44-83 years; mean age, 60 years) during a 13-month period were enrolled. Hepatic MRI, including DWI (b-factors=50, 400, 800 s/mm²) with breath-holding technique of single-shot spin-echo echo-planar imaging (TR/TE=1000/69 ms, average=2) before and after SPIO administration, were retrospectively reviewed by two independent radiologists with a 5-point scale confidence score for each hepatic lesion on pre-contrast DWI (pre-DWI), SPIO-enhanced DWI (SPIO-DWI), and SPIO-enhanced T2*-weighted imaging (SPIO-T2*wI). RESULTS: For all lesions, SPIO-T2*wI showed significantly higher confidence score in the diagnosis of hepatic metastases than pre-contrast or SPIO-DWI regardless of the size of b-factors (p<0.05) with only one exception; using b-factor=50 s/mm², the score of SPIO-T2*wI was still higher than SPIO-DWI but there was no statistical significance given by observer 1 (p=0.730). For the subcentimeter lesions (n=37), SPIO-T2*wI showed the highest score, and using b-factor= 50 or 400 s/mm² SPIO-DWI showed similar confidence scores to SPIO-T2*wI by both observers (p>0.05). Pre-DWI using b-factor=50 sec/mm² was also comparable with SPIO-T2*wI by observer 1 (p=0.060). CONCLUSION: Pre-DWI has a limited value for the assessment of hepatic metastases, however, the repetition of DWI after SPIO injection using small b-factors could complement SPIO-T2*wI, especially for subcentimeter lesions. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 825~833 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Contrast Media*/chemistry | - |
dc.subject.MESH | Diffusion Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Ferric Compounds*/chemistry | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Neoplasms/diagnosis* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neoplasm Metastasis/diagnosis* | - |
dc.title | Diffusion-weighted MR imaging before and after contrast enhancement with superparamagnetic iron oxide for assessment of hepatic metastasis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Hana Kim | - |
dc.contributor.googleauthor | Jeong-Sik Yu | - |
dc.contributor.googleauthor | Dae Jung Kim | - |
dc.contributor.googleauthor | Jae-Joon Chung | - |
dc.contributor.googleauthor | Joo Hee Kim | - |
dc.contributor.googleauthor | Ki Whang Kim | - |
dc.identifier.doi | 22665353 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00951 | - |
dc.contributor.localId | A01089 | - |
dc.contributor.localId | A00345 | - |
dc.contributor.localId | A02500 | - |
dc.contributor.localId | A03712 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 22665353 | - |
dc.subject.keyword | Liver | - |
dc.subject.keyword | metastasis | - |
dc.subject.keyword | diffusion magnetic resonance imaging | - |
dc.subject.keyword | superparamagnetic iron oxide (SPIO) | - |
dc.contributor.alternativeName | Kim, Ki Whang | - |
dc.contributor.alternativeName | Kim, Joo Hee | - |
dc.contributor.alternativeName | Kim, Ha Na | - |
dc.contributor.alternativeName | Yu, Jeong Sik | - |
dc.contributor.alternativeName | Chung, Jae Joon | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hee | - |
dc.contributor.affiliatedAuthor | Kim, Ha Na | - |
dc.contributor.affiliatedAuthor | Kim, Ki Whang | - |
dc.contributor.affiliatedAuthor | Yu, Jeong Sik | - |
dc.contributor.affiliatedAuthor | Chung, Jae Joon | - |
dc.citation.volume | 53 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 825 | - |
dc.citation.endPage | 833 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.53(4) : 825-833, 2012 | - |
dc.identifier.rimsid | 29635 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.