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Current management and future strategies of gastric cancer

Authors
 Joong Ho Lee  ;  Kyung Min Kim  ;  Jae-Ho Cheong  ;  Sung Hoon Noh 
Citation
 YONSEI MEDICAL JOURNAL, Vol.53(2) : 248-257, 2012 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2012
MeSH
Disease Management ; Gastrectomy ; Humans ; Lymph Node Excision ; Stomach Neoplasms/diagnosis* ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/etiology ; Stomach Neoplasms/surgery
Keywords
Stomach neoplasm ; primary prevention ; screening ; gastrectomy ; lymphadenectomy ; biological marker ; molecular therapeutics
Abstract
The overall prognosis of gastric cancer has gradually improved over the past decades with growing awareness of potential carcinogens, surveillance programs and early diagnosis, as well as advances in surgical techniques and multimodality treatments. Nevertheless, the outcome of advanced stage disease still remains poor with currently available treatments, and a worldwide consensus on the standard management thereof has not been established. To improve prognosis and quality of life in gastric cancer patients, both standardization and individualization of managements are imperative. Diagnostic tests and surgical procedures need to be further sophisticated and standardized based on more recent evidences from ongoing and future randomized controlled trials, while comprehensive management should be individualized to each patient. Future challenges lie with how to optimize personalized therapies by deciphering biological complexity of gastric cancer and incorporating molecular biomarkers in clinical practice to forecast prognosis and to guide targeted therapeutics in adjunct to current standards of care.
Files in This Item:
T201202425.pdf Download
DOI
22318810
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Noh, Sung Hoon(노성훈) ORCID logo https://orcid.org/0000-0003-4386-6886
Lee, Joong Ho(이중호)
Cheong, Jae Ho(정재호) ORCID logo https://orcid.org/0000-0002-1703-1781
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92111
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