2 199

Cited 0 times in

Preoperative prediction of the microvascular invasion of hepatocellular carcinoma with diffusion-weighted imaging.

DC FieldValueLanguage
dc.contributor.author김기황-
dc.contributor.author김명진-
dc.contributor.author박미숙-
dc.contributor.author서영주-
dc.contributor.author최진영-
dc.date.accessioned2014-12-19T17:26:42Z-
dc.date.available2014-12-19T17:26:42Z-
dc.date.issued2012-
dc.identifier.issn1527-6465-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91420-
dc.description.abstractThe aim of this study was to investigate whether diffusion-weighted imaging (DWI) could be useful in predicting the microvascular invasion (MVI) of hepatocellular carcinoma (HCC). Sixty-seven surgically proven HCCs from 65 patients (54 men and 11 women with an age range of 35-75 years and a mean age of 56.0 years) were retrospectively analyzed. The signal intensities (SIs) of the lesions on preoperative diffusion-weighted (DW) images were visually categorized as isointense or hyperintense in comparison with the adjacent liver. We also quantitatively measured SIs and apparent diffusion coefficients (ADCs) by drawing regions of interest in HCCs and livers on DW images with b values of 50, 400, and 800 second/mm(2) and on ADC map images. Logistic regression analyses were performed so that we could identify independent predictors of MVI among laboratory and DWI findings. A univariate analysis showed that a histological grade of 3, a larger tumor size, a higher SI ratio on DW images, and a lower ADC value were significantly associated with MVI. A multiple logistic regression analysis showed that a histological grade of 3 and the ADC value were independent predictors of MVI. With a cutoff of 1.11 × 10(-3) mm(2)/second, the ADC value provided a sensitivity of 93.5% and a specificity of 72.2% for the prediction of MVI with an odds ratio of 24.5 (95% confidence interval = 4.14-144.8, P < 0.001). In conclusion, lower ADC values (1.11 × 10(-3) mm(2)/second or less) can be a useful predictor of MVI during the preoperative evaluation of HCC.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfLIVER TRANSPLANTATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCarcinoma, Hepatocellular/blood supply*-
dc.subject.MESHCarcinoma, Hepatocellular/pathology*-
dc.subject.MESHCarcinoma, Hepatocellular/surgery-
dc.subject.MESHDiffusion Magnetic Resonance Imaging/methods*-
dc.subject.MESHFemale-
dc.subject.MESHHepatectomy-
dc.subject.MESHHumans-
dc.subject.MESHLiver Neoplasms/blood supply*-
dc.subject.MESHLiver Neoplasms/pathology*-
dc.subject.MESHLiver Neoplasms/surgery-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMicrovessels/pathology*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPreoperative Care-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHTreatment Outcome-
dc.titlePreoperative prediction of the microvascular invasion of hepatocellular carcinoma with diffusion-weighted imaging.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorYoung Joo Suh-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.contributor.googleauthorJin-Young Choi-
dc.contributor.googleauthorMi-Suk Park-
dc.contributor.googleauthorKi Whang Kim-
dc.identifier.doi22767394-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00345-
dc.contributor.localIdA00426-
dc.contributor.localIdA01463-
dc.contributor.localIdA01892-
dc.contributor.localIdA04200-
dc.relation.journalcodeJ02172-
dc.identifier.eissn1527-6473-
dc.identifier.pmid22767394-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/lt.23502/abstract-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordCarcinoma, Hepatocellular/blood supply*-
dc.subject.keywordCarcinoma, Hepatocellular/pathology*-
dc.subject.keywordCarcinoma, Hepatocellular/surgery-
dc.subject.keywordDiffusion Magnetic Resonance Imaging/methods*-
dc.subject.keywordFemale-
dc.subject.keywordHepatectomy-
dc.subject.keywordHumans-
dc.subject.keywordLiver Neoplasms/blood supply*-
dc.subject.keywordLiver Neoplasms/pathology*-
dc.subject.keywordLiver Neoplasms/surgery-
dc.subject.keywordLogistic Models-
dc.subject.keywordMale-
dc.subject.keywordMicrovessels/pathology*-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPredictive Value of Tests-
dc.subject.keywordPreoperative Care-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordSensitivity and Specificity-
dc.subject.keywordTreatment Outcome-
dc.contributor.alternativeNameKim, Ki Whang-
dc.contributor.alternativeNameKim, Myeong Jin-
dc.contributor.alternativeNamePark, Mi Sook-
dc.contributor.alternativeNameSuh, Young Joo-
dc.contributor.alternativeNameChoi, Jin Young-
dc.contributor.affiliatedAuthorKim, Ki Whang-
dc.contributor.affiliatedAuthorKim, Myeong Jin-
dc.contributor.affiliatedAuthorPark, Mi-Suk-
dc.contributor.affiliatedAuthorSuh, Young Joo-
dc.contributor.affiliatedAuthorChoi, Jin Young-
dc.citation.volume18-
dc.citation.number10-
dc.citation.startPage1171-
dc.citation.endPage1178-
dc.identifier.bibliographicCitationLIVER TRANSPLANTATION, Vol.18(10) : 1171-1178, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.