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The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer
- Authors
- Jieun Kang ; Kathleen R. Jones ; Sungil Jang ; Cara H. Olsen ; Yun-Jung Yoo ; D. Scott Merrell ; Jeong-Heon Cha
- Citation
- JOURNAL OF CLINICAL MICROBIOLOGY, Vol.50(3) : 1082-1085, 2012
- Journal Title
- JOURNAL OF CLINICAL MICROBIOLOGY
- ISSN
- 0095-1137
- Issue Date
- 2012
- MeSH
- Adult ; Aged ; Antigens, Bacterial/genetics ; Asia ; Bacterial Outer Membrane Proteins/genetics* ; Bacterial Proteins/genetics ; Female ; Gene Dosage ; Helicobacter pylori/genetics ; Helicobacter pylori/isolation & purification* ; Helicobacter pylori/pathogenicity* ; Humans ; Male ; Middle Aged ; Stomach Neoplasms/microbiology* ; Virulence Factors/genetics*
- Keywords
- Adult ; Aged ; Antigens, Bacterial/genetics ; Asia ; Bacterial Outer Membrane Proteins/genetics* ; Bacterial Proteins/genetics ; Female ; Gene Dosage ; Helicobacter pylori/genetics ; Helicobacter pylori/isolation & purification* ; Helicobacter pylori/pathogenicity* ; Humans ; Male ; Middle Aged ; Stomach Neoplasms/microbiology* ; Virulence Factors/genetics*
- Abstract
- We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.
- Files in This Item:
- T201200215.pdf Download
- DOI
- 22205793
- Appears in Collections:
- 2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers
- Yonsei Authors
- Kang, Ji Eun(강지은)
Yoo, Yun Jung(유윤정)
https://orcid.org/0000-0002-0045-9597
Jang, Sungil(장성일) https://orcid.org/0000-0001-6144-6899
Cha, Jeong Heon(차정헌) https://orcid.org/0000-0002-9385-2653
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