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The association between the triglyceride to high-density lipoprotein cholesterol ratio with insulin resistance (HOMA-IR) in the general Korean population: based on the National Health and Nutrition Examination Survey in 2007-2009.

Authors
 Jong-Seok Kim  ;  Hee-Taik Kang  ;  Jae-Yong Shim  ;  Hye-Ree Lee 
Citation
 DIABETES RESEARCH AND CLINICAL PRACTICE, Vol.97(1) : 132-138, 2012 
Journal Title
 DIABETES RESEARCH AND CLINICAL PRACTICE 
ISSN
 0168-8227 
Issue Date
2012
MeSH
Asian Continental Ancestry Group* ; Blood Pressure ; Cholesterol, HDL/blood* ; Cross-Sectional Studies ; Female ; Humans ; Insulin Resistance* ; Male ; Middle Aged ; Nutrition Surveys ; Obesity/epidemiology ; Republic of Korea/epidemiology ; Triglycerides/blood* ; Waist Circumference*
Keywords
The triglyceride to high-density lipoprotein cholesterol ratio ; Insulin resistance ; HOMA-IR
Abstract
AIMS: This study explores the association between the ratio of triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) and insulin resistance according to waist circumference in the general Korean population. METHODS: 7623 participants were selected from the Korean National Health and Nutrition Examination Survey (KNHANES) conducted during 2007-2009 and included in this cross-sectional study. Insulin resistance was defined as the values equal to or greater than the 75th percentile of the homeostasis model assessment of insulin resistance (HOMA-IR). RESULTS: Positive correlation was found between the ratio of TG and HDL-C and other variables such as waist circumference, total cholesterol, and HOMA-IR for both men and women. The odds ratios (ORs) (95% confidence interval) for insulin resistance for the highest quartile of TG/HDL-C were 2.48 in men and 3.05 in women. The significant relationship between the TG/HDL-C ratio and insulin resistance was not only maintained across all quartiles of waist circumference but also seemed to be enhanced in the higher quartiles of waist circumference. CONCLUSION: In the general Korean population, there seems to be a linear association between TG/HDL-C ratio and insulin resistance, regardless of degrees of waist circumference.
Full Text
http://www.sciencedirect.com/science/article/pii/S0168822712001568
DOI
22607906
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Hee Taik(강희택)
Kim, Jong Seok(김종석)
Shim, Jae Yong(심재용) ORCID logo https://orcid.org/0000-0002-9561-9230
Lee, Hye Ree(이혜리)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90120
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