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Independent association of TG/HDL-C with urinary albumin excretion in normotensive subjects in a rural Korean population.
DC Field | Value | Language |
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dc.contributor.author | 강희택 | - |
dc.contributor.author | 인요한 | - |
dc.date.accessioned | 2014-12-19T16:40:23Z | - |
dc.date.available | 2014-12-19T16:40:23Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89972 | - |
dc.description.abstract | BACKGROUND: The ratio of triglycerides (TG, mg/dl) to high-density lipoprotein cholesterol (HDL-C, mg/dl) is a reliable indicator of insulin resistance and atherosclerotic diseases in some ethnic groups. This study is performed to examine the association between TG/HDL-C and albuminuria. METHODS: This cross-sectional study included 9094 adult subjects (4091 men, 5003 women) who were enrolled in the Korean Genomic Rural Cohort (KGRC) and aged 40 years or more. Albuminuria was defined as a urine albumin/creatinine ratio ≥ 30 mg/g. Participants were categorized into TG/HDL-C quartile. RESULTS: Compared to the lowest TG/HDL-C quartile (<1.94 in men, <1.71 in women), the odds ratios (ORs) for albuminuria in participants who were categorized in the highest TG/HDL-C quartile (≥ 4.98 in men, ≥ 4.20 in women) were 1.30 (95% CI: 0.97-1.75) and 1.36 (1.03-1.79) in men and women, respectively, when adjusted for blood pressure and other covariates. In normotensive men and women, the ORs for albuminuria in the highest TG/HDL-C quartile were 1.58 (1.04-2.39) and 1.68 (1.15-2.45), respectively, even after fully adjusted. In contrast, TG/HDL-C was not associated with albuminuria in hypertensive subjects. CONCLUSIONS: TG/HDL-C was independently associated with increased prevalence of albuminuria in normotensive rural Korean subjects aged 40 years or more in KGRC. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Albuminuria/physiopathology | - |
dc.subject.MESH | Albuminuria/urine* | - |
dc.subject.MESH | Blood Pressure* | - |
dc.subject.MESH | Cholesterol, HDL/blood* | - |
dc.subject.MESH | Creatinine/urine | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glomerular Filtration Rate | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Rural Population* | - |
dc.subject.MESH | Triglycerides/blood* | - |
dc.title | Independent association of TG/HDL-C with urinary albumin excretion in normotensive subjects in a rural Korean population. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | Hee-Taik Kang | - |
dc.contributor.googleauthor | Jong-Koo Kim | - |
dc.contributor.googleauthor | Jang-Young Kim | - |
dc.contributor.googleauthor | John A. Linton | - |
dc.contributor.googleauthor | Jin-Ha Yoon | - |
dc.contributor.googleauthor | Sang-Baek Koh | - |
dc.identifier.doi | 22037512 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00106 | - |
dc.contributor.localId | A03352 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 22037512 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009898111005821 | - |
dc.subject.keyword | Albuminuria | - |
dc.subject.keyword | High-density lipoprotein cholesterol | - |
dc.subject.keyword | Triglyceride | - |
dc.subject.keyword | Urine albumin to creatinine ratio (UACR) | - |
dc.contributor.alternativeName | Kang, Hee Taik | - |
dc.contributor.alternativeName | Linton, John A. | - |
dc.contributor.affiliatedAuthor | Kang, Hee Taik | - |
dc.contributor.affiliatedAuthor | Linton, John A. | - |
dc.citation.volume | 413 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 319 | - |
dc.citation.endPage | 324 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.413(1-2) : 319-324, 2012 | - |
dc.identifier.rimsid | 32011 | - |
dc.type.rims | ART | - |
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