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Photosensitizer and vancomycin-conjugated novel multifunctional magnetic particles as photoinactivation agents for selective killing of pathogenic bacteria
- Authors
- Kyong-Hoon Choi ; Hye-Jin Lee ; Bong Joo Park ; Kang-Kyun Wang ; Eon Pil Shin ; Jong-Chul Park ; Young Keun Kim ; Min-Kyu Oh ; Yong-Rok Kim
- Citation
- CHEMICAL COMMUNICATIONS, Vol.48(38) : 4591-4593, 2012
- Journal Title
- CHEMICAL COMMUNICATIONS
- ISSN
- 1359-7345
- Issue Date
- 2012
- MeSH
- Animals ; Bacteria/drug effects* ; Cell Line ; Cell Survival/drug effects ; Ferrosoferric Oxide/chemistry ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Magnetite Nanoparticles/chemistry ; Magnetite Nanoparticles/microbiology* ; Mice ; Photosensitizing Agents/chemistry* ; Photosensitizing Agents/pharmacology* ; Surface Properties ; Vancomycin/chemistry*
- Abstract
- Novel multifunctional magnetic particles (MMPs) conjugated with photosensitizer and vancomycin were fabricated by surface modification of Fe(3)O(4) particles. The capacities to target, capture and inactivate pathogenic bacteria and good biocompatibility suggest that the MMPs have great potentials as photodynamic inactivation agents for serious bacterial contamination.
- Appears in Collections:
- 1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
- Yonsei Authors
-
Park, Jong Chul(박종철)
https://orcid.org/0000-0003-0083-5991
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