Cited 51 times in
Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: its assessment by cardiac magnetic resonance
DC Field | Value | Language |
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dc.contributor.author | 이현철 | - |
dc.contributor.author | 이혜정 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 강은석 | - |
dc.contributor.author | 김영진 | - |
dc.contributor.author | 김현민 | - |
dc.contributor.author | 이병완 | - |
dc.contributor.author | 유희태 | - |
dc.contributor.author | 김광준 | - |
dc.date.accessioned | 2014-12-19T16:37:51Z | - |
dc.date.available | 2014-12-19T16:37:51Z | - |
dc.date.issued | 2012 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89892 | - |
dc.description.abstract | BACKGROUND: We used cardiovascular magnetic resonance (CMR) to investigate the association between epicardial adipose tissue (EAT) thickness and silent myocardial ischemia, as well as coronary artery stenosis, in asymptomatic type 2 diabetic patients. METHODS: The study included 100 type 2 diabetic subjects (51 male and 49 female; mean age: 56 ± 7 years). Silent myocardial ischemia, as determined by CMR, was defined as evidence of inducible ischemia or myocardial infarction. Signal reduction or stenosis of ≥ 50% in the vessel diameter was used as the criteria for significant coronary artery stenosis on coronary magnetic resonance (MR) angiography. RESULTS: EAT thickness was positively correlated with body mass index (BMI), waist-to-hip ratio, systolic blood pressure, postprandial glucose, fasting/postprandial triglyceride (TG), serum glycated hemoglobin (HbA1c) level, and homeostasis model assessment of insulin resistance (HOMA-IR) score. Significant coronary artery stenosis was found in 24 patients, while 14 patients had silent myocardial ischemia in CMR (1 with silent myocardial infarction, 11 with inducible ischemia, and 2 with both). EAT thickness was greater in patients who had coronary artery stenosis (13.0 ± 2.6 mm vs. 11.5 ± 2.1 mm, p = 0.01), but did not differ between the subjects with or without silent myocardial ischemia on CMR images (12.8 ± 2.1 vs. 11.7 ± 2.3 mm, p = 0.11). Multivariate logistic regression analysis indicated that EAT thickness was an independent indicator for significant coronary artery stenosis after adjusting for traditional risk factors (OR 1.403, p = 0.026). CONCLUSIONS: Increased EAT thickness assessed by CMR is an independent risk factor for significant coronary artery stenosis in asymptomatic type 2 diabetes. However, EAT thickness was not associated with silent myocardial ischemia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | CARDIOVASCULAR DIABETOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adipose Tissue/pathology* | - |
dc.subject.MESH | Asymptomatic Diseases | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Coronary Stenosis/blood | - |
dc.subject.MESH | Coronary Stenosis/complications | - |
dc.subject.MESH | Coronary Stenosis/diagnosis* | - |
dc.subject.MESH | Coronary Stenosis/pathology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/blood | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/complications* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2/diagnosis | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Magnetic Resonance Angiography* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Myocardial Ischemia/blood | - |
dc.subject.MESH | Myocardial Ischemia/complications | - |
dc.subject.MESH | Myocardial Ischemia/diagnosis* | - |
dc.subject.MESH | Myocardial Ischemia/pathology | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Pericardium/pathology* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.title | Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: its assessment by cardiac magnetic resonance | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hyun Min Kim | - |
dc.contributor.googleauthor | Kwang Joon Kim | - |
dc.contributor.googleauthor | Hye-Jeong Lee | - |
dc.contributor.googleauthor | Hee Tae Yu | - |
dc.contributor.googleauthor | Jae Hoon Moon | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Byung-Wan Lee | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.identifier.doi | 10.1186/1475-2840-11-83 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A01110 | - |
dc.contributor.localId | A02796 | - |
dc.contributor.localId | A03320 | - |
dc.contributor.localId | A00727 | - |
dc.contributor.localId | A00317 | - |
dc.relation.journalcode | J00460 | - |
dc.identifier.eissn | 1475-2840 | - |
dc.identifier.pmid | 22809408 | - |
dc.subject.keyword | Epicardial adipose tissue | - |
dc.subject.keyword | Cardiovascular magnetic resonance | - |
dc.subject.keyword | Silent ischemia | - |
dc.subject.keyword | Coronary artery stenosis | - |
dc.subject.keyword | Type 2 diabetes | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lee, Hye Jeong | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Kim, Young Jin | - |
dc.contributor.alternativeName | Kim, Hyun Min | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Min | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Hye Jeong | - |
dc.contributor.affiliatedAuthor | Kim, Young Jin | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Joon | - |
dc.citation.volume | 11 | - |
dc.citation.startPage | 83 | - |
dc.identifier.bibliographicCitation | CARDIOVASCULAR DIABETOLOGY, Vol.11 : 83, 2012 | - |
dc.identifier.rimsid | 31968 | - |
dc.type.rims | ART | - |
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