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Small hypervascular hepatocellular carcinomas: value of diffusion-weighted imaging compared with "washout" appearance on dynamic MRI.

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dc.contributor.author김기황-
dc.contributor.author김대중-
dc.contributor.author김주희-
dc.contributor.author유정식-
dc.contributor.author정재준-
dc.date.accessioned2014-12-19T16:36:00Z-
dc.date.available2014-12-19T16:36:00Z-
dc.date.issued2012-
dc.identifier.issn0007-1285-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89834-
dc.description.abstractOBJECTIVE: To compare the value of diffusion-weighted MRI (DWI) with the venous "washout" appearance during dynamic MRI for the assessment of small arterial hypervascular lesions in cirrhotic liver. METHODS: After exclusion of benign hypervascular lesions, including haemangiomas and subcapsular non-tumorous arterioportal shunts, indicated by typical imaging features, a total of 109 small arterial hypervascular lesions (0.5-3.0 cm in the longest diameter) in 65 patients with cirrhosis who underwent gadopentetate dimeglumine-enhanced dynamic MRI and DWI (b=50, 400, 800 s mm(-2)) at 1.5 T during a 16-month period were retrospectively analysed to determine the presence of venous washout during dynamic imaging or sustained hyperintensity upon increasing the b factor size on DWI. RESULTS: Among the 99 hypervascular hepatocellular carcinomas (HCCs), sustained hyperintensity on DWI (92/99, 93%) was more prevalent than the washout appearance (72/99, 72%) on dynamic MRI (p<0.001). Depending on the lesion size, subcentimetre-sized HCCs had a significantly lower prevalence of venous washout (13/30, 43%) than the sustained hyperintensity on DWI (27/30, 90%) (p=0.001). In all 10 hypervascular benign conditions, there was no venous washout on dynamic MRI and no sustained hyperintensity on DWI. Sensitivity and specificity for diagnosis of hypervascular HCCs were 92.9% and 100% in DWI and 72% and 100% in dynamic MRI, respectively. CONCLUSION: Compared with the venous washout during dynamic imaging, DWI provides more reliable information in the MRI assessment of small hypervascular HCCs, distinguishing them from atypical hypervascular benign or pseudolesions. DWI could complement the early diagnosis of small hypervascular HCCs that do not display venous washout during dynamic imaging.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfBRITISH JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHCarcinoma, Hepatocellular/blood supply-
dc.subject.MESHCarcinoma, Hepatocellular/diagnosis*-
dc.subject.MESHDiffusion Magnetic Resonance Imaging/methods*-
dc.subject.MESHEarly Detection of Cancer/methods-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLiver Neoplasms/blood supply-
dc.subject.MESHLiver Neoplasms/diagnosis*-
dc.subject.MESHMagnetic Resonance Angiography/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.titleSmall hypervascular hepatocellular carcinomas: value of diffusion-weighted imaging compared with "washout" appearance on dynamic MRI.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorD J Kim-
dc.contributor.googleauthorJ-S Yu-
dc.contributor.googleauthorJ H Kim-
dc.contributor.googleauthorJ-J Chung-
dc.contributor.googleauthorK W Kim-
dc.identifier.doi22573299-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00951-
dc.contributor.localIdA00345-
dc.contributor.localIdA00369-
dc.contributor.localIdA02500-
dc.contributor.localIdA03712-
dc.relation.journalcodeJ00417-
dc.identifier.eissn1748-880X-
dc.identifier.pmid22573299-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordAged, 80 and over-
dc.subject.keywordCarcinoma, Hepatocellular/blood supply-
dc.subject.keywordCarcinoma, Hepatocellular/diagnosis*-
dc.subject.keywordDiffusion Magnetic Resonance Imaging/methods*-
dc.subject.keywordEarly Detection of Cancer/methods-
dc.subject.keywordFemale-
dc.subject.keywordHumans-
dc.subject.keywordLiver Neoplasms/blood supply-
dc.subject.keywordLiver Neoplasms/diagnosis*-
dc.subject.keywordMagnetic Resonance Angiography/methods*-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordRetrospective Studies-
dc.contributor.alternativeNameKim, Ki Whang-
dc.contributor.alternativeNameKim, Dae Jung-
dc.contributor.alternativeNameKim, Joo Hee-
dc.contributor.alternativeNameYu, Jeong Sik-
dc.contributor.alternativeNameChung, Jae Joon-
dc.contributor.affiliatedAuthorKim, Joo Hee-
dc.contributor.affiliatedAuthorKim, Ki Whang-
dc.contributor.affiliatedAuthorKim, Dae Jung-
dc.contributor.affiliatedAuthorYu, Jeong Sik-
dc.contributor.affiliatedAuthorChung, Jae Joon-
dc.citation.volume85-
dc.citation.number1018-
dc.citation.startPage879-
dc.citation.endPage886-
dc.identifier.bibliographicCitationBRITISH JOURNAL OF RADIOLOGY, Vol.85(1018) : 879-886, 2012-
dc.identifier.rimsid31934-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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