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Application of the Western-based adjuvant online model to Korean colon cancer patients; a single institution experience.

Authors
 Minkyu Jung  ;  Geon Woo Kim  ;  Inkyung Jung  ;  Joong Bae Ahn  ;  Jae Kyung Roh  ;  Sun Young Rha  ;  Hyun Cheol Chung  ;  Nam Kyu Kim  ;  Tae Il Kim  ;  Sang Joon Shin 
Citation
 BMC Cancer, Vol.12 : 471-471, 2012 
Journal Title
 BMC Cancer 
ISSN
 1471-2407 
Issue Date
2012
Abstract
BACKGROUND: Adjuvant Online (AOL) is web-accessible risk-assessment model that predicts the mortality and the benefits of adjuvant therapy (http://www.newadjuvantonline.com). AOL has never been validated for Asian colon cancer patients. METHODS: Using the Yonsei Tumor Registry database, patients who were treated within the Yonsei University Health System between 1990 and 2005 for T1-4, N0-2, and M0 colon cancer were included in the calculations for survival. Observed and predicted 5-year overall survival was compared for each patient. RESULTS: The median age of the study population of 1431 patients was 60 years (range, 15-87 years), and the median follow-up duration was 7.9 years (range, 0.06-19.8 years). The predicted 5-year overall survival rate (77.7%) and observed survival (79.5%) was not statistically different (95% Confidential interval, 76.3-81.5) in all patients. Predicted outcomes were within 95% confidential interval of observed survival in both stage II and III disease, including most demographic and pathologic subgroups. Moreover, AOL more accurately predicted OS for patients with stage II than stage III. CONCLUSIONS: AOL tended to offer reliable prediction for 5-year overall survival and could be used as a decision making tool for adjuvant treatment in Korean colon cancer patients whose prognosis is similar to other Asian patients.
Files in This Item:
T201203430.pdf Download
DOI
10.1186/1471-2407-12-471
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김남규(Kim, Nam Kyu) ORCID logo https://orcid.org/0000-0003-0639-5632
김태일(Kim, Tae Il) ORCID logo https://orcid.org/0000-0003-4807-890X
노재경(Roh, Jae Kyung)
라선영(Rha, Sun Young) ORCID logo https://orcid.org/0000-0002-2512-4531
신상준(Shin, Sang Joon) ORCID logo https://orcid.org/0000-0001-5350-7241
안중배(Ahn, Joong Bae) ORCID logo https://orcid.org/0000-0001-6787-1503
정민규(Jung, Min Kyu) ORCID logo https://orcid.org/0000-0001-8281-3387
정인경(Jung, Inkyung) ORCID logo https://orcid.org/0000-0003-3780-3213
정현철(Chung, Hyun Cheol) ORCID logo https://orcid.org/0000-0002-0920-9471
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89773
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