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Association of plasma osteoprotegerin levels with stroke severity and functional outcome in acute ischaemic stroke patients

DC FieldValueLanguage
dc.contributor.author김영대-
dc.contributor.author김진권-
dc.contributor.author남정모-
dc.contributor.author남효석-
dc.contributor.author박지혜-
dc.contributor.author송태진-
dc.contributor.author양승희-
dc.contributor.author이옥희-
dc.contributor.author이혜선-
dc.contributor.author허지회-
dc.date.accessioned2014-12-19T16:32:31Z-
dc.date.available2014-12-19T16:32:31Z-
dc.date.issued2012-
dc.identifier.issn1354-750X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89725-
dc.description.abstractOsteoprotegerin (OPG) is known to regulate processes involved in vascular injury and inflammation. We investigated the relationship between plasma OPG levels and stroke subtype, stroke severity at admission and functional outcome at 3 months in 172 patients with acute ischaemic stroke. Patients with large artery atherosclerosis and those with multiple causes had higher plasma OPG levels than patients with lacune. Increased plasma OPG levels were independently associated with more severe stroke and poor functional outcome. These results suggest pleiotropic roles of OPG in mediating atherosclerosis and ischaemic brain injury. OPG is a potential biomarker for predicting neurologic outcome in stroke.-
dc.description.statementOfResponsibilityopen-
dc.format.extent738~744-
dc.relation.isPartOfBIOMARKERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcute Disease-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers/blood*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIschemia/complications-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHOsteoprotegerin/blood*-
dc.subject.MESHPrognosis-
dc.subject.MESHRisk Factors-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHStroke/blood*-
dc.subject.MESHStroke/diagnosis-
dc.subject.MESHStroke/etiology-
dc.titleAssociation of plasma osteoprotegerin levels with stroke severity and functional outcome in acute ischaemic stroke patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorTae-Jin Song-
dc.contributor.googleauthorJinkwon Kim-
dc.contributor.googleauthorSeung-Hee Yang-
dc.contributor.googleauthorJi Hye Park-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorChung Mo Nam-
dc.contributor.googleauthorOk-Hee Lee-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorJi Hoe Heo-
dc.identifier.doi23030274-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00702-
dc.contributor.localIdA01012-
dc.contributor.localIdA01264-
dc.contributor.localIdA01273-
dc.contributor.localIdA02073-
dc.contributor.localIdA02296-
dc.contributor.localIdA02970-
dc.contributor.localIdA04369-
dc.contributor.localIdA03312-
dc.contributor.localIdA01694-
dc.relation.journalcodeJ00311-
dc.identifier.eissn1366-5804-
dc.identifier.pmid23030274-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/1354750X.2012.727027-
dc.subject.keywordStroke-
dc.subject.keywordosteoprotegerin-
dc.subject.keywordfunctional outcome-
dc.subject.keywordstroke severity-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.alternativeNameKim, Jin Kwon-
dc.contributor.alternativeNameNam, Jung Mo-
dc.contributor.alternativeNameNam, Hyo Suk-
dc.contributor.alternativeNamePark, Ji Hye-
dc.contributor.alternativeNameSong, Tae Jin-
dc.contributor.alternativeNameYang, Seung Hee-
dc.contributor.alternativeNameLee, Ok Hee-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.contributor.affiliatedAuthorKim, Young Dae-
dc.contributor.affiliatedAuthorKim, Jin Kwon-
dc.contributor.affiliatedAuthorNam, Jung Mo-
dc.contributor.affiliatedAuthorNam, Hyo Suk-
dc.contributor.affiliatedAuthorSong, Tae Jin-
dc.contributor.affiliatedAuthorYang, Seung Hee-
dc.contributor.affiliatedAuthorLee, Ok Hee-
dc.contributor.affiliatedAuthorHeo, Ji Hoe-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorPark, Ji Hye-
dc.citation.volume17-
dc.citation.number8-
dc.citation.startPage738-
dc.citation.endPage744-
dc.identifier.bibliographicCitationBIOMARKERS, Vol.17(8) : 738-744, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Yonsei Integrative Research Institute for Cerebral & Cardiovascular Disease (뇌심혈관질환융합연구사업단) > 1. Journal Papers

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