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Short communication: factors influencing time to CD4(+) T cell counts >200 cells/mm(3) in HIV-infected individuals with CD4(+) T cell <50 cells/mm(3) at the time of starting combination antiretroviral therapy

Authors
 Nam Su Ku  ;  Young Goo Song  ;  Sang Hoon Han  ;  Sun Bean Kim  ;  Hye-won Kim  ;  Su Jin Jeong  ;  Chang Oh Kim  ;  June Myung Kim  ;  Jun Yong Choi 
Citation
 AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol.28(12) : 1594-1597, 2012 
Journal Title
 AIDS RESEARCH AND HUMAN RETROVIRUSES 
ISSN
 0889-2229 
Issue Date
2012
MeSH
Adult ; Aged ; Anti-Retroviral Agents/administration & dosage* ; Antiretroviral Therapy, Highly Active* ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology* ; Case-Control Studies ; Female ; HIV Infections/drug therapy* ; HIV Infections/immunology* ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Treatment Outcome
Keywords
Adult ; Aged ; Anti-Retroviral Agents/administration & dosage* ; Antiretroviral Therapy, Highly Active* ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology* ; Case-Control Studies ; Female ; HIV Infections/drug therapy* ; HIV Infections/immunology* ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Treatment Outcome
Abstract
We evaluated factors influencing time to CD4(+) T cell counts >200 cells/mm(3) in HIV-infected individuals with CD4(+) T cell <50 cells/mm(3) starting combination antiretroviral therapy (cART). We included a total of 29 patients on successful cART for more than 1 year. In a logistic regression model, higher pre-cART CD4(+) T cell counts were significantly associated with shorter time to CD4(+) T cell counts >200cells/mm(3) in HIV-infected individuals with baseline CD4(+) T cell <50 cells/mm(3). In survival analysis, patients having higher pre-cART CD4(+) T cell counts, especially 40-49 cells/mm(3), were at significantly higher risk of achieving CD4(+) T cell counts >200 cells/mm(3).
Files in This Item:
T201205221.pdf Download
DOI
22632127
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ku, Nam Su(구남수) ORCID logo https://orcid.org/0000-0002-9717-4327
Kim, Sun Bean(김선빈)
Kim, June Myung(김준명)
Kim, Chang Oh(김창오) ORCID logo https://orcid.org/0000-0002-0773-5443
Kim, Hye Won(김혜원)
Song, Young Goo(송영구) ORCID logo https://orcid.org/0000-0002-0733-4156
Jeong, Su Jin(정수진) ORCID logo https://orcid.org/0000-0003-4025-4542
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
Han, Sang Hoon(한상훈) ORCID logo https://orcid.org/0000-0002-4278-5198
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89393
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