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Additional value of dual-energy CT to differentiate between benign and malignant mediastinal tumors: An initial experience

DC FieldValueLanguage
dc.contributor.author이혜정-
dc.contributor.author최병욱-
dc.contributor.author허진-
dc.contributor.author홍유진-
dc.contributor.author김영진-
dc.date.accessioned2014-12-18T10:03:04Z-
dc.date.available2014-12-18T10:03:04Z-
dc.date.issued2013-
dc.identifier.issn0720-048X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89320-
dc.description.abstractOBJECTIVES: To investigate the feasibility of dual-energy computed tomography (DECT) in differentiating malignant from benign mediastinal tumors. MATERIALS AND METHODS: We prospectively enrolled 25 patients (14 males; mean age: 56.7 years) who had suspected mediastinal tumors on chest radiography or non-contrast chest computed tomography (CT). All patients underwent a two-phase DECT using gemstone spectral imaging (GSI) mode (GE HD750). For the quantitative analysis, two investigators measured the following parameters of the tumors in the early and the delayed phases: CT attenuation value in Hounsfield units (HU) and iodine concentration (mg/ml). Pathological results were used for a final diagnosis. Statistical analyses were performed using the Fisher's exact test and the Mann-Whitney t-test. RESULTS: 10 patients (40%) had benign pathology, while 15 (60%) had malignant pathology. The iodine concentration measurements were significantly different between benign and malignant tumors both in the early phase (1.38 mg/ml vs. 2.41 mg/ml, p=0.001) and in the delayed phase (1.52 mg/ml vs. 2.84 mg/ml, p=0.001), while mean attenuation values were not significantly different in both phases (57.8 HU vs. 69.1 HU, p=0.067 and 67.4 HU vs. 78.4 HU, p=0.086, respectively). CONCLUSIONS: Dual-energy CT using a quantitative analytic methodology can be used to differentiate between benign and malignant mediastinal tumors.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfEUROPEAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMediastinal Neoplasms/diagnostic imaging*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPilot Projects-
dc.subject.MESHRadiography, Dual-Energy Scanned Projection/methods*-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHTomography, X-Ray Computed/methods*-
dc.titleAdditional value of dual-energy CT to differentiate between benign and malignant mediastinal tumors: An initial experience-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorSeung Hyun Lee-
dc.contributor.googleauthorJin Hur-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorYoo Jin Hong-
dc.contributor.googleauthorByoung Wook Choi-
dc.identifier.doi10.1016/j.ejrad.2013.05.040-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03320-
dc.contributor.localIdA00727-
dc.contributor.localIdA04059-
dc.contributor.localIdA04370-
dc.contributor.localIdA04422-
dc.relation.journalcodeJ00845-
dc.identifier.eissn1872-7727-
dc.identifier.pmid23820175-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0720048X13002969-
dc.subject.keywordBenign neoplasm-
dc.subject.keywordDifferentiation-
dc.subject.keywordDual-energy computed tomography-
dc.subject.keywordMalignant neoplasm-
dc.subject.keywordMediastinal neopla는-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameHur, Jin-
dc.contributor.alternativeNameHong, Yoo Jin-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorKim, Young Jin-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorHur, Jin-
dc.contributor.affiliatedAuthorHong, Yoo Jin-
dc.rights.accessRightsnot free-
dc.citation.volume82-
dc.citation.number11-
dc.citation.startPage2043-
dc.citation.endPage2049-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF RADIOLOGY, Vol.82(11) : 2043-2049, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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