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Cited 6 times in

NSCLC Subtype Prediction Using Cytologic Fluid Specimens From Needle Aspiration Biopsies

DC FieldValueLanguage
dc.contributor.author김영진-
dc.contributor.author김희영-
dc.contributor.author심효섭-
dc.contributor.author이지원-
dc.contributor.author이혜정-
dc.contributor.author조응혁-
dc.contributor.author최병욱-
dc.contributor.author허진-
dc.contributor.author홍유진-
dc.date.accessioned2014-12-18T09:56:21Z-
dc.date.available2014-12-18T09:56:21Z-
dc.date.issued2013-
dc.identifier.issn0002-9173-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89113-
dc.description.abstractThis study evaluated the diagnostic usefulness of tumor marker concentrations in cytologic fluids (CF) for subtyping non-small cell lung cancer (NSCLC) and assessed the relationship between fluorine-18-fluorodeoxyglucose ((18)F-FDG) uptake with serum and CF tumor marker levels. This prospective study included 88 patients diagnosed with adenocarcinoma or squamous cell carcinoma (SCC). Cytokeratin-19 fragment (CYFRA 21-1), carcinoembryonic antigen (CEA), and squamous cell carcinoma antigen (SCCA) concentrations in the CF samples were correlated with serum tumor marker concentrations, (18)F-FDG uptake, and NSCLC subtype. Fifty-eight patients were diagnosed with adenocarcinoma. Multivariate analysis revealed higher CF and serum SCCA levels; smoking status predicted SCC from adenocarcinoma. CF SCCA showed the highest accuracy (83%) in distinguishing between SCC and adenocarcinoma. CF samples obtained during routine needle aspiration biopsy procedure contain tumor marker levels sufficient to distinguish between SCC and adenocarcinoma; CF SCCA had the highest diagnostic accuracy.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfAMERICAN JOURNAL OF CLINICAL PATHOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAntigens, Neoplasm/analysis-
dc.subject.MESHArea Under Curve-
dc.subject.MESHBiomarkers, Tumor/analysis*-
dc.subject.MESHBiopsy, Needle-
dc.subject.MESHBody Fluids/chemistry*-
dc.subject.MESHCarcinoembryonic Antigen/analysis-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung/diagnosis*-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung/diagnostic imaging-
dc.subject.MESHCarcinoma, Non-Small-Cell Lung/surgery-
dc.subject.MESHCytodiagnosis-
dc.subject.MESHFemale-
dc.subject.MESHFluorodeoxyglucose F18-
dc.subject.MESHHumans-
dc.subject.MESHKeratin-19/analysis-
dc.subject.MESHLung Neoplasms/diagnosis*-
dc.subject.MESHLung Neoplasms/diagnostic imaging-
dc.subject.MESHLung Neoplasms/surgery-
dc.subject.MESHMale-
dc.subject.MESHPositron-Emission Tomography-
dc.subject.MESHROC Curve-
dc.subject.MESHRadiopharmaceuticals-
dc.subject.MESHSensitivity and Specificity-
dc.titleNSCLC Subtype Prediction Using Cytologic Fluid Specimens From Needle Aspiration Biopsies-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Nuclear Medicine (핵의학)-
dc.contributor.googleauthorArthur Cho-
dc.contributor.googleauthorJin Hur-
dc.contributor.googleauthorYoo Jin Hong-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorHee Yeong Kim-
dc.contributor.googleauthorJi Won Lee-
dc.contributor.googleauthorHyo Sup Shim-
dc.contributor.googleauthorByoung Wook Choi-
dc.identifier.doi10.1309/AJCPYOJYG56UNBSZ-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00727-
dc.contributor.localIdA03320-
dc.contributor.localIdA03204-
dc.contributor.localIdA01213-
dc.contributor.localIdA02219-
dc.contributor.localIdA03887-
dc.contributor.localIdA04059-
dc.contributor.localIdA04370-
dc.contributor.localIdA04422-
dc.relation.journalcodeJ00076-
dc.identifier.eissn1943-7722-
dc.identifier.pmid23429366-
dc.subject.keywordNeddle aspiration biopsy-
dc.subject.keywordCytologic fluid-
dc.subject.keywordSerum-
dc.subject.keywordNon–small cell lung cancer-
dc.subject.keywordCYFRA 21-1-
dc.subject.keywordCEA-
dc.subject.keywordSCCA-
dc.subject.keywordFluorine-18-fluorodeoxyglucose-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.alternativeNameKim, Hee Yeong-
dc.contributor.alternativeNameShim, Hyo Sup-
dc.contributor.alternativeNameLee, Ji Won-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameCho, Arthur Eung Hyuck-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameHur, Jin-
dc.contributor.alternativeNameHong, Yoo Jin-
dc.contributor.affiliatedAuthorKim, Young Jin-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorLee, Ji Won-
dc.contributor.affiliatedAuthorKim, Hee Yeong-
dc.contributor.affiliatedAuthorShim, Hyo Sup-
dc.contributor.affiliatedAuthorCho, Arthur Eung Hyuck-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorHur, Jin-
dc.contributor.affiliatedAuthorHong, Yoo Jin-
dc.rights.accessRightsfree-
dc.citation.volume139-
dc.citation.number3-
dc.citation.startPage309-
dc.citation.endPage316-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF CLINICAL PATHOLOGY, Vol.139(3) : 309-316, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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