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Comparison of the therapeutic effects of ultrasound-guided platelet-rich plasma injection and dry needling in rotator cuff disease: a randomized controlled trial

 Dong-wook Rha  ;  Gi-Young Park  ;  Yong-Kyun Kim  ;  Min Tae Kim  ;  Sang Chul Lee 
 CLINICAL REHABILITATION, Vol.27(2) : 113-122, 2013 
Journal Title
Issue Date
Adult ; Aged ; Cohort Studies ; Double-Blind Method ; Female ; Humans ; Injections, Intra-Articular ; Male ; Middle Aged ; Needles ; Platelet-Rich Plasma* ; Range of Motion, Articular ; Recovery of Function ; Rotator Cuff Injuries* ; Shoulder Pain/etiology ; Shoulder Pain/physiopathology ; Shoulder Pain/prevention & control* ; Tendinopathy/etiology ; Tendinopathy/physiopathology ; Tendinopathy/therapy* ; Treatment Outcome
Rotator cuff ; platelet-rich plasma ; injection ; controlled trial
OBJECTIVE: To compare the effects of platelet-rich plasma injection with those of dry needling on shoulder pain and function in patients with rotator cuff disease. DESIGN: A single-centre, prospective, randomized, double-blinded, controlled study. SETTING: University rehabilitation hospital. PARTICIPANTS: Thirty-nine patients with a supraspinatus tendon lesion (tendinosis or a partial tear less than 1.0 cm, but not a complete tear) who met the inclusion criteria recruited between June 2010 and February 2011. INTERVENTION: Two dry needling procedures in the control group and two platelet-rich plasma injections in the experimental group were applied to the affected shoulder at four-week intervals using ultrasound guidance. MEASUREMENTS: The Shoulder Pain and Disability Index, passive range of motion of the shoulder, a physician global rating scale at the six-month follow-up, adverse effects monitoring and an ultrasound measurement were used as outcome measures. RESULTS: The clinical effect of the platelet-rich plasma injection was superior to the dry needling from six weeks to six months after initial injection (P < 0.05). At six months the mean Shoulder Pain and Disability Index was 17.7 ± 3.7 in the platelet-rich plasma group versus 29.5 ± 3.8 in the dry needling group (P < 0.05). No severe adverse effects were observed in either group. CONCLUSIONS: Autologous platelet-rich plasma injections lead to a progressive reduction in the pain and disability when compared to dry needling. This benefit is certainly still present at six months after treatment. These findings suggest that treatment with platelet-rich plasma injections is safe and useful for rotator cuff disease.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Rha, Dong Wook(나동욱) ORCID logo https://orcid.org/0000-0002-7153-4937
Lee, Sang Chul(이상철) ORCID logo https://orcid.org/0000-0002-6241-7392
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