SLA 처리된 임플란트 표면에서 상온대기압 공기 플라즈마가 세포활성에 미치는 영향

Abstract

Surface properties of titanium implants are known as important factors for successful osseointegration. The purpose of this research is to apply recently highlighted non-thermal atmospheric pressure plasma jet (NTAPPJ) on sand blast, large grit, acid etching(SLA) treated Titaniumi surface to improve the hydrophilicity and cellular response. The change in the chemical binding state of SLA-treated Ti before and after the NTAPPJ treatment were determined using field emission scanning electron icroscope, optical surface roughness system, X-ray photoelectron spectroscope, and water contact angle measuring system. MC3T3-E1 cells (murine osteoblastic cell line) attachments and proliferations were examined by the PrestoBlue reagent. This study found that the compressed air-based NTAPPJ treatment on SLA-treated Ti surface significantly increased the hydrophilicity and MC3T3-E1 cell attachments and proliferations. These results suggested that compressed air-based NTAPPJ treatment on the SLA-treated Ti surface had an effect on increasing attachments and proliferations of MC3T3-E1 cell for better osseointegration in vitro.