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Acid neutralizing, mechanical and physical properties of pit and fissure sealants containing melt-derived 45S5 bioactive glass

 Song-Yi Yang  ;  Yin-Zhu Piao  ;  Sung-Min Kim  ;  Yong-Keun Lee  ;  Kyoung-Nam Kim  ;  Kwang-Mahn Kim 
 Dental Materials, Vol.29(12) : 1228-1235, 2013 
Journal Title
 Dental Materials 
Issue Date
OBJECTIVES: The aim of this study was to examine the effects of 45S5 bioactive glass (BAG) on the acid neutralizing, mechanical and physical properties of pit and fissure sealants. METHODS: 45S5BAG (<25 μm) was mixed with the silanized glass (180 ± 30 nm) and added into a resin matrix [Bis-GMA/TEGDMA 50/50 (wt%) containing 1% of DMAEMA/CQ 2:1 (wt%)] with varying filler proportions; 0% 45S5BAG+50% glass (BAG0); 12.5% 45S5BAG+37.5% glass (BAG12.5); 25% 45S5BAG+25% glass (BAG25); 37.5% 45S5BAG+12.5% glass (BAG37.5); and 50% 45S5BAG+0% glass (BAG50). To evaluate the acid neutralizing properties, specimens were immersed in lactic acid solution (pH 4.0). Then, the change in pH and the time required to raise the pH from 4.0 to 5.5 were measured. In addition, flexural strength, water sorption and solubility were analyzed. RESULTS: The acid neutralizing properties of each group exhibited increasing pH values as more 45S5BAG was added, and the time required to raise the pH from 4.0 to 5.5 became shorter as the proportion of 45S5BAG increased (P<0.05). Additionally, the flexural strength decreased according to the increasing proportions of 45S5BAG added (P<0.05). Water sorption showed an increasing trend with increasing proportions of 45S5 BAG added (P<0.05). However, the solubility results were similar among the groups (P>0.05), except for BAG50. SIGNIFICANCE: The novel pit and fissure sealants neutralized the acid solution (pH 4.0) and exhibited appropriate mechanical and physical properties. Therefore, these compounds are suitable candidates for caries-inhibiting dental materials.
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2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Periodontal Tissue Regeneration (치주조직재생연구소) > 1. Journal Papers
Yonsei Authors
김경남(Kim, Kyoung Nam)
김광만(Kim, Kwang Mahn) ORCID logo https://orcid.org/0000-0002-5235-0294
김성민(Kim, Sung Min)
박은주(Piao, Yin Zhu)
양송이(Yang, Song Yi)
이용근(Lee, Yong Keun)
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