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Adiponectin as a new paradigm for approaching Alzheimer's disease

Authors
 Juhyun Song  ;  Jong Eun Lee 
Citation
 Anatomy and Cell Biology, Vol.46(4) : 229-234, 2013 
Journal Title
 Anatomy and Cell Biology 
ISSN
 2093-3665 
Issue Date
2013
Keywords
Adiponectin ;  Alzheimer's disease ; Brain insulin system ; Cognitive impairment
Abstract
Adiponectin is an adipocytokine released by the adipose tissue and has multiple roles in the immune system and in the metabolic syndromes such as cardiovascular disease, Type 2 diabetes, obesity and also in the neurodegenerative disorders including Alzheimer's disease. Adiponectin regulates the sensitivity of insulin, fatty acid catabolism, glucose homeostasis and anti-inflammatory system through various mechanisms. Previous studies demonstrated that adiponectin modulates memory and cognitive impairment and contributes to the deregulated glucose metabolism and mitochondrial dysfunction observed in Alzheimer's disease. Here, we aim to summarize recent studies that suggest the potential correlation between adiponectin and Alzheimer's disease.
Files in This Item:
T201304271.pdf Download
DOI
10.5115/acb.2013.46.4.229
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anatomy (해부학교실) > 1. Journal Papers
Yonsei Authors
Song, Ju Hyun(송주현)
Lee, Jong Eun(이종은) ORCID logo https://orcid.org/0000-0001-6203-7413
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88599
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