4 245

Cited 18 times in

Surface modification of biphasic calcium phosphate scaffolds by non-thermal atmospheric pressure nitrogen and air plasma treatment for improving osteoblast attachment and proliferation

Authors
 Yu-Ri Choi  ;  Jae-Sung Kwon  ;  Doo-Hoon Song  ;  Eun Ha Choi  ;  Yong-Keun Lee  ;  Kyoung-Nam Kim  ;  Kwang-Mahn Kim 
Citation
 THIN SOLID FILMS, Vol.547 : 235-240, 2013 
Journal Title
 THIN SOLID FILMS 
ISSN
 0040-6090 
Issue Date
2013
Keywords
Non-thermal atmospheric plasma ; Surface energy ; Surface modification ; Hydrophilic ; Scaffold ; Biphasic scaffold ; Osteoblast
Abstract
Surface modifications induced by non-thermal plasma have been used extensively in biomedical applications. The attachment and proliferation of osteoblast cells are important in bone tissue engineering using scaffolds. Hence the effect of non-thermal plasma on hydroxyapatite/β-tri-calcium phosphate (HA/β-TCP) scaffolds in terms of improving osteoblast attachment and proliferation was investigated. Experimental groups were treated with non-thermal plasma for 10 min and 20 min and a control group was not treated with non-thermal plasma. For surface chemistry analysis, X-ray photoelectron spectroscopy (XPS) analysis was carried out. The hydrophilicity was determined from contact angle measurement on the surface. Atomic force microscopy analysis (AFM) was used to test the change in surface roughness and cell attachment and proliferation were evaluated using MC3T3-E1 osteoblast cells. XPS spectra revealed a decreased amount of carbon on the surface of the plasma-treated sample. The contact angle was also decreased following plasma treatment, indicating improved hydrophilicity of plasma-treated surfaces compared to the untreated disc. A significant increase in MC3T3E-1 cell attachment and proliferation was noted on plasma-treated samples as compared to untreated specimens. The results suggest that non-thermal atmospheric pressure nitrogen and air plasma treatments provide beneficial surface characteristics on HA/β-TCP scaffolds.
Full Text
http://www.sciencedirect.com/science/article/pii/S0040609013002873
DOI
10.1016/j.tsf.2013.02.038
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Jae-Sung(권재성) ORCID logo https://orcid.org/0000-0001-9803-7730
Kim, Kyoung Nam(김경남)
Kim, Kwang Mahn(김광만) ORCID logo https://orcid.org/0000-0002-5235-0294
Choi, Yu Ri(최유리)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88522
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse