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Flecainide-Associated Bradycardia-Dependent Torsade de Pointes: Another Potential Mechanism of Proarrhythmia

Authors
 HAN SANG KIM  ;  HUI-NAM PAK  ;  JONG SEOUNG PARK  ;  SUNG SOON KIM 
Citation
 PACE - Pacing and Clinical Electrophysiology, Vol.36(3) : 84-86, 2013 
Journal Title
 PACE - Pacing and Clinical Electrophysiology 
ISSN
 0147-8389 
Issue Date
2013
Abstract
Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia. We present a patient who experienced recurrent syncope due to bradycardia-dependent torsade de pointes (TdP) associated with flecainide-related bradycardia and QT prolongation. Bradycardia-dependent TdP with QT prolongation can be considered as one of mechanisms of flecainide-induced proarrhythmia.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1540-8159.2010.02935.x/abstract
DOI
10.1111/j.1540-8159.2010.02935.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김성순(Kim, Sung Soon)
김한상(Kim, Han Sang) ORCID logo https://orcid.org/0000-0002-6504-9927
박종성(Park, Jong Seoung)
박희남(Pak, Hui Nam) ORCID logo https://orcid.org/0000-0002-3256-3620
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88480
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