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Comparison of optical quality parameters and ocular aberrations after wavefront-guided laser in-situ keratomileusis versus wavefront-guided laser epithelial keratomileusis for myopia

 Kwanghyun Lee  ;  Ji Min Ahn  ;  Eung Kweon Kim  ;  Tae-im Kim 
 Graefes Archive for Clinical and Experimental Ophthalmology, Vol.251(9) : 2163-2169, 2013 
Journal Title
 Graefes Archive for Clinical and Experimental Ophthalmology 
Issue Date
Aberrometry ; Adult ; Cornea/physiopathology* ; Corneal Wavefront Aberration/physiopathology* ; Female ; Glare ; Humans ; Keratectomy, Subepithelial, Laser-Assisted/methods* ; Keratomileusis, Laser In Situ/methods* ; Lasers, Excimer/therapeutic use* ; Light ; Male ; Middle Aged ; Myopia/physiopathology ; Myopia/surgery* ; Postoperative Period ; Refraction, Ocular/physiology* ; Scattering, Radiation ; Visual Acuity/physiology* ; Young Adult
Optical quality ; Higher order aberrations ; Ocular scattering ; Refractive surgery
BACKGROUND: To compare optical quality, ocular scattering, and higher-order aberrations (HOAs) after laser in-situ keratomileusis (LASIK) versus laser epithelial keratomileusis (LASEK). METHODS: A total of 47 eyes from 47 participants who had undergone LASIK (group I) or LASEK (group II) procedure at least 6 months prior were enrolled. Ocular aberrations and modulation transfer function (MTF) values measured using iTrace, a ray-tracing type aberrometer, were compared to MTF (modulation transfer function) cut-off values, Strehl ratio, and objective indices of scattering obtained using the Objective Quality Analysis System II (OQAS II). RESULTS: There was no significant correlation between the postoperative optical quality parameters and the HOAs between both groups. In group I, the MTF cut-off value was significantly correlated with cylinder refraction (p = 0.037), and the objective scattering index (OSI) was positively correlated with spherical equivalent (p = 0.023). In group II, there was a statistically significant correlation between the OSI and achieved refractive correction (p = 0.001). Regression analysis showed that the OSI was the most significant predictor of MTF cut-off values after refractive surgery. Additionally, MTF values measured by OQAS were significantly lower than those measured by iTrace without correlation. CONCLUSION: Optical quality after refractive surgery may be influenced by not only ocular aberrations but also by scattering. Even though the accuracies of the machines used in this study to measure optical quality have yet to be proven, this study showed limited correlation among the values measured using the two different machines after refractive surgery. Therefore, for more generalized evaluation of visual function after refractive surgery, more advanced optical devices still need to be developed.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Tae Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Ahn, Ji Min(안지민)
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