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Relationship between leukoaraiosis and menopause in healthy middle-aged women

DC FieldValueLanguage
dc.contributor.author서석교-
dc.contributor.author이병석-
dc.contributor.author이상민-
dc.contributor.author정인경-
dc.contributor.author정태섭-
dc.contributor.author조시현-
dc.contributor.author최영식-
dc.date.accessioned2014-12-18T09:04:47Z-
dc.date.available2014-12-18T09:04:47Z-
dc.date.issued2013-
dc.identifier.issn0015-0282-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87494-
dc.description.abstractOBJECTIVE: To investigate the relationship between leukoaraiosis (LA) and menopause in healthy middle-aged women. DESIGN: A retrospective cohort study. SETTING: Health promotion center of a university hospital. PATIENT(S): We studied 262 healthy pre- and postmenopausal women ages 41-60 years who visited the health promotion center for a routine health checkup. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): LA is defined as diffuse white matter abnormalities on computed tomography or magnetic resonance imaging (MRI). LA was assessed by examining MRIs and using the rating scale of the Atherosclerosis Risk in Communities Study. Logistic regression analysis was performed to examine associations between LA and menopause. RESULT(S): Women with LA had a significantly higher age than women without LA. Elevated blood pressure (≥ 130/85 mm Hg) and low high-density lipoprotein cholesterol (<50 mg/dL) were frequent abnormal findings in women with LA. The proportion of menopause was significantly higher in women with LA than in those without LA. Menopause was independently associated with the presence of LA (adjusted odds ratio, 2.24; 95% confidence interval, 1.10, 4.60) after adjusting for confounding variables. CONCLUSION(S): Menopause was significantly associated with LA. Loss of estrogen may play an important role in the development of LA.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfFERTILITY AND STERILITY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHBlood Pressure/physiology-
dc.subject.MESHCholesterol/blood-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHHealth-
dc.subject.MESHHumans-
dc.subject.MESHLeukoaraiosis/diagnostic imaging-
dc.subject.MESHLeukoaraiosis/epidemiology*-
dc.subject.MESHMagnetic Resonance Imaging-
dc.subject.MESHMenopause/physiology*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHTomography, X-Ray Computed-
dc.titleRelationship between leukoaraiosis and menopause in healthy middle-aged women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorSeok Kyo Seo-
dc.contributor.googleauthorInkyung Jung-
dc.contributor.googleauthorSang Min Lee-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorYoung Sik Choi-
dc.contributor.googleauthorTae Sub Chung-
dc.contributor.googleauthorByung Seok Lee-
dc.identifier.doi10.1016/j.fertnstert.2013.03.047-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01888-
dc.contributor.localIdA02795-
dc.contributor.localIdA03693-
dc.contributor.localIdA03751-
dc.contributor.localIdA03846-
dc.contributor.localIdA04114-
dc.contributor.localIdA02815-
dc.relation.journalcodeJ00894-
dc.identifier.eissn1556-5653-
dc.identifier.pmid23622889-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0015028213004639-
dc.subject.keywordLeukoaraiosis-
dc.subject.keywordestrogen-
dc.subject.keywordmenopause-
dc.contributor.alternativeNameSeo, Seok Kyo-
dc.contributor.alternativeNameLee, Byung Seok-
dc.contributor.alternativeNameLee, Sang Min-
dc.contributor.alternativeNameJung, In Kyung-
dc.contributor.alternativeNameChung, Tae Sub-
dc.contributor.alternativeNameCho, Si Hyun-
dc.contributor.alternativeNameChoi, Young Sik-
dc.contributor.affiliatedAuthorSeo, Seok Kyo-
dc.contributor.affiliatedAuthorLee, Byung Seok-
dc.contributor.affiliatedAuthorJung, In Kyung-
dc.contributor.affiliatedAuthorChung, Tae Sub-
dc.contributor.affiliatedAuthorCho, Si Hyun-
dc.contributor.affiliatedAuthorChoi, Young Sik-
dc.contributor.affiliatedAuthorLee, Sang Min-
dc.rights.accessRightsnot free-
dc.citation.volume100-
dc.citation.number2-
dc.citation.startPage500-
dc.citation.endPage504-
dc.identifier.bibliographicCitationFERTILITY AND STERILITY, Vol.100(2) : 500-504, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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