3 111

Cited 4 times in

Achieving recommended low density lipoprotein cholesterol goals and the factors associated with target achievement of hypercholesterolemia patients with rosuvastatin in primary care

Authors
 Jung Ah Lee ; Sung Sunwoo ; Chul-Min Kim ; Byung Yeon Yu ; Yun Jun Yang ; Sang Yeoup Lee ; Dong Hyuk Sin ; Kyung-Chae Park ; Hee-Cheol Kang ; Han Jin Oh ; Young Sik Kim 
Citation
 Current Medical Research and Opinion, Vol.29(7) : 751~760, 2013 
Journal Title
 Current Medical Research and Opinion 
ISSN
 0300-7995 
Issue Date
2013
Abstract
OBJECTIVE: Hypercholesterolemia is a major risk factor for cardiovascular disease and requires continuous management. The role of primary physicians in this regard is important, yet the factors associated with successful lipid lowering treatments in primary clinics have not been clearly identified. We aimed to evaluate the rate of successful hypercholesterolemia treatment in Korean primary care, and to identify the factors associated with achieving low density lipoprotein cholesterol (LDL-C) targets. METHODS: We prospectively recruited and retrospectively assessed 1851 Korean patients with hypercholesterolemia who visited family physicians and were prescribed rosuvastatin for the first time. LDL-C lowering targets, defined according to NCEP ATP III guidelines, were evaluated at 6 months after the first prescription. The factors associated with achieving these targets were also assessed. RESULTS: Overall, 87.6% of our participants attained their LDL-C goals. In multiple logistic regression analysis, good adherence to medication was strongly associated with the achievement of target LDL-C levels, whereas higher cardiovascular risk factors including diabetes (in both sexes), low high density lipoprotein, and current smoking status (in males), and hypertension (in females) were related to LDL-C target level failures. CONCLUSION: Our observations of the short period for hypercholesterolemia in Korean primary care has revealed that the rate of achieving target LDL-C levels was high in these patients, whereas patients at higher risk for cardiovascular disease tended to have lower LDL-C achievement outcomes. Primary care physicians should pay more attention to patients showing higher cardiovascular risk and stress the need for good adherence and management regimens in these individuals.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87031
DOI
10.1185/03007995.2013.802683
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Family Medicine
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://informahealthcare.com/doi/abs/10.1185/03007995.2013.802683
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse