4 330

Cited 19 times in

The effects of non-thermal atmospheric pressure plasma jet on cellular activity at SLA-treated titanium surfaces

 Eun-Jung Lee  ;  Jae-Sung Kwon  ;  Soo-Hyuk Uhm  ;  Doo-Hoon Song  ;  Yong Hee Kim  ;  Eun Ha Choi  ;  Kyoung-Nam Kim 
 Current Applied Physics, Vol.13(S1) : 36-41, 2013 
Journal Title
 Current Applied Physics 
Issue Date
Titanium (Ti) is a primary material used for dental implants, and the sandblasted, large-grit, and acid-etched (SLA) surface treatment is commonly used on titanium to promote early osseointegration. Despite their benefits, SLA-treated Ti surfaces are disadvantaged by their hydrophobic property, and much research has been performed to address this problem. In current study, we hypothesized the effects of a nitrogen-based non-thermal atmospheric pressure plasma jet (NTAPPJ) treatment on SLA-treated Ti would increase hydrophilicity and cellular activity. Samples with and without the NTAPPJ treatment were analyzed using a field emission scanning electron microscope, optical surface roughness system, X-ray photoelectron spectroscope, and water contact angle measuring system. MC3T3-E1 cells (murine osteoblastic cell line) attachments and proliferations were examined by the MTT and BrdU colorimetry assay. Cell immunofluorescent microscopic images were observed by a confocal laser scanning microscope for a morphological analysis. This study found that the nitrogen-based NTAPPJ treatment on SLA-treated Ti significantly increased the hydrophilicity and MC3T3-E1 cell attachments and proliferations. Hence, it was concluded that an additional procedure of nitrogen-based NTAPPJ treatment just prior to implantation of SLA-treated Ti into oral defect sites could improve the success of dental implant surgery.
Full Text
Appears in Collections:
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실)
1. Journal Papers (연구논문) > 5. Research Institutes (연구소) > Research Center for Orofacial Hard Tissue Regeneration (구강악안면경조직재생연구센터)
Yonsei Authors
권재성(Kwon, Jae-Sung) ORCID logo https://orcid.org/0000-0001-9803-7730
김경남(Kim, Kyoung Nam)
송두훈(Song, Doo Hoon)
엄수혁(Uhm, Soo Hyuk)
이은정(Lee, Eun Jung)
RIS (EndNote)
XLS (Excel)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.