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A Case of Immunoglobulin E Mediated Anaphylaxis to Levodropropizine

Authors
 Kyung Hee Park  ;  Il Seon Yun  ;  Soo-Young Choi  ;  Jae-Hyun Lee  ;  Chein-Soo Hong  ;  Jung-Won Park 
Citation
 Yonsei Medical Journal, Vol.54(1) : 262-264, 2013 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2013
MeSH
Adolescent ; Anaphylaxis/chemically induced* ; Anaphylaxis/immunology* ; Antitussive Agents/adverse effects* ; Bronchial Provocation Tests ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin E/immunology* ; Propylene Glycols/adverse effects* ; Skin Tests
Keywords
Levodropropizine ; anaphylaxis ; drug hypersensitivity
Abstract
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).
Files in This Item:
T201301056.pdf Download
DOI
10.3349/ymj.2013.54.1.262
Appears in Collections:
1. College of Medicine (의과대학) > Medical Research Center (임상의학연구센터) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Kyung Hee(박경희) ORCID logo https://orcid.org/0000-0003-3605-5364
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Yun, Il Seon(윤일선)
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
Choi, Soo Young(최수영)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86707
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