Cited 1 times in

Sinonasal seromucinous hamartoma: a single institution case series combined with a narrative review of the literature

Authors
 Chan Hee Kim  ;  Hyung-Ju Cho  ;  Chang-Hoon Kim  ;  Min-Seok Rha 
Citation
 EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, Vol.281(10) : 5311-5317, 2024-10 
Journal Title
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
ISSN
 0937-4477 
Issue Date
2024-10
MeSH
Hamartoma* / diagnosis ; Hamartoma* / pathology ; Hamartoma* / surgery ; Humans ; Nasal Cavity / pathology ; Nasal Polyps / complications ; Nasal Polyps / diagnosis ; Nasal Polyps / pathology ; Nasal Polyps / surgery ; Nose Diseases / diagnosis ; Nose Diseases / pathology ; Nose Diseases / surgery ; Paranasal Sinus Diseases / diagnosis ; Paranasal Sinus Diseases / pathology ; Paranasal Sinus Diseases / surgery
Keywords
Hamartoma ; Respiratory epithelial adenomatoid hamartoma ; Seromucinous hamartoma ; Sinonasal tumor
Abstract
PurposeThis study aimed to investigate the clinical and histopathological characteristics of sinonasal seromucinous hamartomas (SHs).MethodsEight patients with sinonasal SH and treated at a tertiary hospital between November 2005 and September 2023 were included. Additionally, a systematic review of published articles was conducted, analyzing 48 cases of SH described in the literature.ResultsAmong the eight patients treated at our institution, tumors originated from the posterior nasal cavity in four patients and middle turbinate and middle meatus were the primary origin in two patients each. Coexistence of inflammatory nasal polyps (NPs) was observed in four cases. Histopathologically, four patients exhibited focal respiratory epithelial adenomatoid hamartoma (REAH) features, and low-grade dysplasia was found in one patient. A combined analysis with previous literature revealed that 46.3% of all cases originated in the anterior nasal cavity. The proportions of cases accompanied by NPs and those with focal REAH features were 20.5% and 39.1%, respectively. Additionally, the frequencies of cases exhibiting dysplastic features (5.4%) and recurrence (2.1%) were low. Remarkably, tumors originating from the anterior region tended to have a higher frequency of dysplasia than those originating from the posterior region, although this difference was not statistically significant (p = 0.0996).ConclusionPatients with sinonasal SH showed favorable treatment outcomes following surgical resection. Focal REAH features and accompanying NPs were frequently observed. A substantial proportion of cases originate in the anterior nasal cavity, and these tumors may exhibit a high tendency for dysplasia.
Full Text
https://link.springer.com/article/10.1007/s00405-024-08759-x
DOI
10.1007/s00405-024-08759-x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chang Hoon(김창훈) ORCID logo https://orcid.org/0000-0003-1238-6396
Rha, Min-Seok(나민석) ORCID logo https://orcid.org/0000-0003-1426-7534
Cho, Hyung Ju(조형주) ORCID logo https://orcid.org/0000-0002-2851-3225
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/200846
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links