Cited 0 times in

Clinical characteristics and risk factors for right-sided infective endocarditis in Korea: a 12-year retrospective cohort study

Authors
 Yongseop Lee  ;  Jung Ho Kim  ;  Jung Ah Lee  ;  Sang Min Ahn  ;  Min Han  ;  Jin Young Ahn  ;  Su Jin Jeong  ;  Jun Yong Choi  ;  Joon-Sup Yeom  ;  Seung Hyun Lee  ;  Nam Su Ku 
Citation
 SCIENTIFIC REPORTS, Vol.14(1) : 10466, 2024-05 
Journal Title
SCIENTIFIC REPORTS
Issue Date
2024-05
MeSH
Adult ; Aged ; Endocarditis* / epidemiology ; Endocarditis* / microbiology ; Endocarditis* / mortality ; Endocarditis, Bacterial / epidemiology ; Endocarditis, Bacterial / microbiology ; Endocarditis, Bacterial / mortality ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Republic of Korea / epidemiology ; Retrospective Studies ; Risk Factors ; Staphylococcal Infections / epidemiology ; Staphylococcal Infections / microbiology ; Staphylococcus aureus / isolation & purification ; Staphylococcus aureus / pathogenicity ; Tertiary Care Centers
Abstract
Right-sided infective endocarditis (RSIE) is less common than left-sided infective endocarditis (LSIE) and exhibits distinct epidemiological, clinical, and microbiological characteristics. Previous studies have focused primarily on RSIE in patients with intravenous drug use. We investigated the characteristics and risk factors for RSIE in an area where intravenous drug use is uncommon. A retrospective cohort study was conducted at a tertiary hospital in South Korea. Patients diagnosed with infective endocarditis between November 2005 and August 2017 were categorized into LSIE and RSIE groups. Of the 406 patients, 365 (89.9%) had LSIE and 41 (10.1%) had RSIE. The mortality rates were 31.7% in the RSIE group and 31.5% in the LSIE group (P = 0.860). Patients with RSIE had a higher prevalence of infection with Staphylococcus aureus (29.3% vs. 13.7%, P = 0.016), coagulase-negative staphylococci (17.1% vs. 6.0%, P = 0.022), and gram-negative bacilli other than HACEK (12.2% vs. 2.2%, P = 0.003). Younger age (adjusted odds ratio [aOR] 0.97, 95% confidence interval [CI] 0.95-0.99, P = 0.006), implanted cardiac devices (aOR 37.75, 95% CI 11.63-141.64, P ≤ 0.001), and central venous catheterization (aOR 4.25, 95% CI 1.14-15.55, P = 0.029) were independent risk factors for RSIE. Treatment strategies that consider the epidemiologic and microbiologic characteristics of RSIE are warranted.
Files in This Item:
T202404416.pdf Download
DOI
10.1038/s41598-024-60638-x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Ku, Nam Su(구남수) ORCID logo https://orcid.org/0000-0002-9717-4327
Kim, Jung Ho(김정호) ORCID logo https://orcid.org/0000-0002-5033-3482
Ahn, Sang Min(안상민)
Ahn, Jin Young(안진영) ORCID logo https://orcid.org/0000-0002-3740-2826
Yeom, Joon Sup(염준섭) ORCID logo https://orcid.org/0000-0001-8940-7170
Lee, Seung Hyun(이승현) ORCID logo https://orcid.org/0000-0002-0311-6565
Lee, Yongseop(이용섭)
Lee, Jung Ah(이정아)
Jeong, Su Jin(정수진) ORCID logo https://orcid.org/0000-0003-4025-4542
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/200178
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links